Tag: United Kingdom Site Content

FDA’s Fast-Track Approval Exposed as Lax, in Need of Reform

Since the US Food and Drug Administration (FDA) established its accelerated drug approval pathway 28 years ago, more than 2 in 5 drugs granted fast-track...

Cryptococcal Meningitis: Single-Dose Regimen Noninferior

A single high dose of the antifungal agent liposomal amphotericin B (L-AmB; AmBisome, Gilead Sciences), with a background regimen of flucytosine and fluconazole, is noninferior...

Pfizer, AZ Vaccines Effective Against Delta, After 2 Doses: Study

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Pfizer-BioNTech and AstraZeneca vaccines — the primary vaccine options in...

Widely Prescribed Meds Ineffective for Low Back Pain?

Despite being widely prescribed, muscle relaxants are largely ineffective for low back pain, new research suggests. Results of a large systematic review and meta-analysis of...

Early Heparin Treatment Linked to Lower COVID-19 Mortality

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Early treatment with low-molecular-weight heparin (LMWH) reduces the risk for death...

Short-Acting Beta Agonist Overuse ‘a Global Public Health Issue’

About one third of asthma patients have high use of short-acting beta agonists (SABAs) in Europe across all severity levels, said Santiago Quirce, MD, PhD,...

IV Iron Can Save Costs in HF With Iron Deficiency in Analysis

Intravenous iron therapy was predicted to be highly cost-effective or even cost-saving when used in high-risk, iron-deficient patients with heart failure (HF) in each of...

Oncologist Accused of Inappropriate Treatment ‘Provided Exceptional Care’

MANCHESTER—Leading oncologist Professor Justin Stebbing has told a medical tribunal he provided “exceptional standards of care” to a cancer patient he’s accused of giving chemotherapy...

Diet Rich in Omega-3s Linked to Fewer Migraines, Less Pain

A diet rich in omega-3 fatty acids reduces the frequency and intensity of monthly migraine attacks, a new study suggests. In this interventional study, a...

Is Chemo Dose Too Low?

Patients with colorectal cancer (CRC) who are also obese have a poorer survival than those who are not obese. A new study suggests that they...

Antibiotic Link to Rise in Early Onset Colon Cancer?

Exposure to antibiotics appears to be associated with the development of colon cancer, particularly in younger people, and could be contributing to the increase in...

Novel Liver Dialysis Device May Safely Curb ACLF

An investigational liver dialysis device (DIALIVE) was associated with significantly greater survival of patients with acute-on-chronic liver failure (ACLF), compared with the standard of care...

‘Treat Youth With Gender Dysphoria as Individuals’

Young people with gender dysphoria should be considered as individuals rather than fall into an age-defined bracket when assessing their understanding to consent to hormone...

Key Driver of Fish Oil’s Antidepressant Effects Revealed

A key molecular mechanism underpinning the anti-inflammatory, antidepressant, and neuroprotective effects of omega-3 fatty acids has been identified.   In findings that could lead to...

Inexpensive Dye Tracks Digestive Transit Time

When it comes to measuring gut transit time, blue dye could be a cost-effective and simple alternative to other, more burdensome methods. The approach, which...

Real-world PCSK9i Data in FH Reveal Conundrum of Reimbursement

Patients with familial hypercholesterolemia (FH), particularly those with heterozygous FH, see their low-density-lipoprotein (LDL) cholesterol levels slashed with evolocumab (Repatha) and maintained out to 2...

Free UK Tool Could Help Guide COVID Care for Cancer Patients

An online support tool for healthcare professionals that recommends whether to admit or discharge a cancer patient with COVID-19, based on their risk of a...

Pfizer Vaccine Protects Less Against India Variant

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. June 4, 2021 — The Pfizer COVID-19 vaccine produces lower levels...

Both Higher Alcohol Intake and Genetic Predisposition Tied to CVD

Cardiovascular disease risk is associated with alcohol intake in general, but variations in risk exist with levels of intake, based on data from a genetic-based...

Texas Standoff Embodies US Battle Over COVID Vaccines

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. There is an escalating fight between Houston Methodist Hospital and wary...

Large Vessel Stroke Linked to AstraZeneca COVID Vaccine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The first cases of large vessel arterial occlusion strokes linked to...

This Scientist Is Auctioning Off His DNA and Says Yours is Valuable Too

George Church’s genes are making history again. The Harvard geneticist was one of the first people to ever have his genome sequenced, and now he...

Main Causes of Food-Induced Anaphylaxis Identified

Allergen disclosure legislation accurately covers the main triggers of anaphylaxis in different countries, according to a systematic review of food anaphylaxis studies. This “first global...

Rituximab Benefits Seen in Neuropsychiatric Lupus

Patients with neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) seem to benefit from rituximab (Rituxan) therapy, according to data from the British Isles Lupus Assessment...

Widen Use of General Anesthesia in End-of-Life Care, Say Experts

General anesthesia should be an option for patients at the end of life as a means of easing the physical and mental distress that can...