Tag: renal insufficiency

Dapagliflozin Safe, Protective in Advanced Kidney Disease

Patients with stage 4 chronic kidney disease (CKD) who were in the DAPA-CKD trial had cardiorenal benefits from dapagliflozin that were similar to those of...

Building a Better Predictive Model for Progression to Kidney Failure

NEW YORK (Reuters Health) – A new risk equation can accurately estimate the risk of chronic kidney disease (CKD) progressing to end-stage kidney disease (ESKD),...

Intensive BP-Lowering for Brain Bleeds Potentially Deadly in CKD

Treating intracranial hemorrhage (ICH) with intensive blood-pressure control is potentially deadly in patients with impaired kidney function, new research shows. A post-hoc analysis from the...

FDA Approves Finerenone for Slowing CKD in Type 2 Diabetes

The US Food and Drug Administration (FDA) approved finerenone (Kerendia), the first agent from a new class of nonsteroidal mineralocorticoid receptor antagonists (MRAs), on July...

Prominent Nephrologist, Mount Sinai Chair of Medicine Dies

Dr Barbara T. Murphy Barbara T. Murphy, MD, renowned nephrologist and professor of medicine at Mount Sinai School of Medicine in New York City, has...

Worse Survival With Recurrent AIH After Transplant

Autoimmune hepatitis that recurs following a liver transplant can impair both graft survival and overall survival, results of a large international study showed. Among 736...

New Transplant Policy Doesn’t Benefit All States

The introduction of the new kidney allocation policy in the US initiated by the Organ Procurement and Transplantation Network (OPTN) may not benefit all states...

Pharmacist + App Cuts Errors, Hospitalization After Transplant

A pharmacist-led intervention that involves use of a smartphone app with home monitoring significantly reduced medication errors, adverse events, and hospitalizations among kidney transplant patients,...

Task Force Reviewing Race Modifier in eGFR Issues Interim Report

The race coefficient now used in calculating estimated glomerular filtration rate (eGFR) in US patients who self-identify as Black will soon change, says a task...

Difelikefalin Safe, Effective for Kidney Disease-Associated Pruritus

Difelikefalin, an investigational intravenous (IV) drug for treating itch (pruritus) in patients with end-stage renal disease on hemodialysis, was safe and effective in two parallel...

Disturbances in Kidney Function Persist After AKI in COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Patients who develop acute kidney injury (AKI) while hospitalized with COVID-19...

‘Major Update’ of BP Guidance for Kidney Disease

The new 2021 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline for blood pressure management for adults with chronic kidney disease (CKD) who are...

Blood Test Predicts Organ Rejection Risk After Kidney Transplant

A functional immunologic assay that could easily be incorporated into routine laboratory work can predict which patients are at high risk for rejection of their...

Missed Visits During Pandemic Cause ‘Detrimental Ripple Effects’

More than one third of adults aged 18-64 years in the United States delayed or went without medical care because of efforts by patients or...

Upsides, Downsides for TAVR, Minimally Invasive AVR

NEW YORK (Reuters Health) – Minimally invasive aortic valve replacement (miAVR) seems to be associated with a lower risk of midterm mortality, while transcatheter aortic...

Radial-to-Backup Artery Switch Adds Limited Risk in ACS PCI

There’s a price to pay for a failed radial artery attempt in invasively managed patients with acute coronary syndrome (ACS), but it may not be...

Springboard Needed to Boost Access to Living Donor Kidney Transplants

A new study indicates numerous ways in which transplant teams can try to reduce disparities that currently mean that Black patients are far less likely...

Did Unrecognized Cardiac Amyloidosis Hinder Recent HFpEF Trials?

Screening for cardiac amyloidosis and excluding patients with cardiac amyloidosis from trials of new therapies for heart failure with preserved ejection fraction (HFpEF) may increase...

Race Modifier Means Black Patients Miss Out on Kidney Transplants

New evidence further confirms that use of the race coefficient when calculating estimated glomerular filtration rate (eGFR) in Black patients with chronic kidney disease (CKD)...

Medicare Coverage of Kidney Transplant Drugs Is Extended

A newly passed US law ensures, starting in 2023, that for Medicare patients who receive a kidney transplant, insurance coverage of immunosuppressant drugs that prevent...

Acute Kidney Injury With COVID-19 Seems to Be Declining in US

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Among US veterans hospitalized with COVID-19, about one third experienced acute...

New CREDENCE Data Support SGLT2 Inhibitor Use in Advanced CKD

In a post-hoc analysis of the CREDENCE study, there were no safety signals when the sodium-glucose cotransporter 2 (SGLT2) inhibitor canagliflozin (Invokana, Janssen) was continued...

Nearly 10% of Hospitalized Patients With COVID-19 Readmitted

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. About one in 11 patients discharged after COVID-19 treatment is readmitted...

New eGFR Equation ‘Less Biased’ by Age, Kidney Function; Some Disagree

A new equation for estimating glomerular filtration rate (eGFR), a measure of kidney function, shows improved accuracy and precision compared with commonly used equations. The...

New Guidelines Address Diabetes Management in Kidney Disease

A new guideline from the Kidney Disease: Improving Global Outcomes (KDIGO) group addressing issues around diabetes management in patients with chronic kidney disease (CKD) has...