Tag: pruritis

Expert Shares Practical Considerations for Dupilumab Treatment

Clinicians who struggle to get dupilumab approved for their patients with moderate to severe atopic dermatitis (AD) are not alone. This scenario was illustrated in...

Topical Ruxolitinib Found Safe, Effective in 52-Week AD Study

After treatment with ruxolitinib cream for 52 weeks, between 60% and 80% of atopic dermatitis patients maintained clear or almost clear skin, with no safety...

Genital Skin Exams in Girls: Advice From an Expert

Genital skin exams in girls must be conducted with special care and alertness for signs of abuse, a dermatologist told colleagues at the American Academy of Dermatology...

Emollient Data Discouraging for Atopic Dermatitis Prevention

Emollients don’t prevent atopic dermatitis (AD), but they might have untapped potential as treatment, two new studies suggest. The results of a prevention study, in...

Novel S1P-Receptor Modulator Shows Promise in Phase 2b AD Trial

A novel, highly selective oral sphingosine 1-phosphate (S1P)–receptor modulator showed promise as a treatment for atopic dermatitis (AD) in a 12-week phase 2b trial, according...

Systematic Approach Helps Manage Skin Disorder-Related Pain

For pain related to skin disorders, dermatologists should generally consider management as their direct responsibility without referrals, according to an expert who outlined his strategies...

Study Enhances Understanding of Prurigo Nodularis

Patients with prurigo nodularis tend to make a greater number of visits to health care specialists and are burdened by a greater number of medical...

Difelikefalin Safe, Effective for Kidney Disease-Associated Pruritus

Difelikefalin, an investigational intravenous (IV) drug for treating itch (pruritus) in patients with end-stage renal disease on hemodialysis, was safe and effective in two parallel...

Peanut Sublingual Immunotherapy Feasible and Effective in Toddlers

Sublingual immunotherapy for the treatment of peanut allergy is safe and effective, even in children as young as age 1 year. In a double-blind, placebo-controlled,...

Delusional Infestation Surges During COVID-19 Pandemic

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Psychiatrists with expertise in delusional infestation have some advice for dermatologists,...

Expert Offers Clinical Pearls on Leg Ulcer Therapy

Chronic leg ulcers of all types feature a significant inflammatory component for which medical compression therapy is absolutely the best form of anti-inflammatory therapy, Elena...

Curbing Itch Intensity, Frequency in Children With Severe Eczema

Dupilumab treatment with concomitant topical corticosteroids provided rapid and sustained improvement in itch intensity and frequency in children aged 6-11 years with severe atopic dermatitis....

Doctors Underreport Side Effects of Breast Irradiation

There is a substantial mismatch between patient and physician reports of toxicity during radiotherapy for breast cancer, according to an analysis of nearly 10,000 U.S....

Improvements in Chronic Hand Eczema Seen With Oral Gusacitinib

Gusacitinib, a novel oral inhibitor of multiple inflammatory pathways, achieved rapid and clinically meaningful improvement in corticosteroid-refractory moderate to severe chronic hand eczema in a...

GLIMMER of Hope for Itch in Primary Biliary Cholangitis

Patients with primary biliary cholangitis experienced rapid improvements in itch and quality of life after treatment with linerixibat in a randomized placebo-controlled trial of the...

Birch Bark Derivative Effective for Epidermolysis Bullosa

A gel derived from birch bark is the first topical medication ever tested in the treatment of epidermolysis bullosa (EB) to heal wounds faster than...

EMA Panel Backs Peanut Allergy Desensitizing Powder Palforzia

The European Medicines Agency’s (EMA’s) Committee for Medicinal Products for Human Use (CHMP) recommended on October 15 that marketing authorization be granted for Palforzia (Aimmune...

How to Relieve One of the Itchiest Vulvar Conditions

A three-step approach may help relieve itch in patients with lichen simplex chronicus, “one of the itchiest conditions that we ever see on the vulva,”...

Novel Oral Drug Improves Sunlight Tolerance

Dersimelagon, a novel once-daily oral selective melanocortin-1 receptor agonist, significantly boosted sunlight tolerance in patients with erythropoietic protoporphyria in a multicenter, phase 2, randomized trial,...

Set Up Your Hyperhidrosis Patients for Treatment Success

When children and adolescents first present to George Hightower, MD, PhD, with suspected primary hyperhidrosis, he tries to gauge their level of impairment and distress....

What We Know and Don’t Know

Right now, my workup includes nasal swab PCR for COVID, and IgG and IgM serology if available. We have IgG easily...