Tag: monoclonal antibody

Antibody Prevents Malaria in New Trial

A new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to 9 months in people who were...

Biologics for Asthma Also Improve Chronic Rhinosinusitis

Biologics used as an asthma treatment also appear to improve symptoms of coexisting chronic rhinosinusitis in some patients, according to results from a real-world study...

2 Sets of Guidelines Disagree

With two sets of Clostridioides difficile recommendations being published within a month of each other, clinicians may find themselves trying to reconcile some of the...

EC Approves Cemiplimab for Advanced or Metastatic BCC

The European Commission (EC) has approved cemiplimab (Libtayo) for the treatment of adults with locally advanced or metastatic basal cell carcinoma (BCC) who progressed on —...

Rituximab Superior to Mycophenolate Mofetil in Pemphigus Vulgaris Study

Mycophenolate mofetil, commonly used as a first-line corticosteroid-sparing agent for moderate to severe cases of the autoimmune blistering skin condition pemphigus vulgaris, has been found...

Immunotherapy Likely New Standard in Advanced Esophageal Cancer

Nivolumab (Opdivo) plus chemotherapy and nivolumab plus ipilimumab (Yervoy) were superior to standard chemotherapy in improving overall survival in patients with advanced esophageal squamous cell...

Lower Steroid Dose Proves Effective for New-Onset ANCA Vasculitis

A reduced dose of prednisolone plus rituximab was as effective as a conventionally high dose in treating patients with newly diagnosed antineutrophil cytoplasmic antibody (ANCA)–associated...

Antibiotic Cut ANCA-Vasculitis Infection Risk With Rituximab

The serious infection risk associated with rituximab treatment for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is high but can be offset by co-prescribing co-trimoxazole, data...

Rituximab Benefits Seen in Neuropsychiatric Lupus

Patients with neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) seem to benefit from rituximab (Rituxan) therapy, according to data from the British Isles Lupus Assessment...

Some MS Treatments May Heighten COVID Risk

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. When it comes to SARS-CoV-2 infection among patients with multiple sclerosis...

Tralokinumab Gets Nod for Atopic Dermatitis in Europe

On Friday, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) issued a positive opinion for the IL-13 inhibitor...

Ublituximab Plus Ibrutinib for CLL

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease associated with several known genetic abnormalities, including 17p deletion (del[17p]), 11q deletion (del[11q]), and TP53 gene...

FDA Revokes Emergency Use of Solo Bamlanivimab for COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The US Food and Drug Administration (FDA) has granted Eli Lilly’s request...

Certain DMTs in MS May Attenuate COVID-19 Vaccines

Dr Amit Bar-Or COVID-19 vaccines are considered safe for patients with multiple sclerosis (MS), a neurologist told colleagues, but those who are on disease-modifying therapy...

Novel Agent Shows Promise Against Cat Allergy

One dose of the novel agent, REGN1908-1909 (Regeneron Pharmaceuticals) resulted in a rapid and durable reduction in cat-allergen-induced bronchoconstriction in cat-allergic subjects with mild asthma....

Tocilizumab May Improve Lung Function in Early Systemic Sclerosis

Treatment with tocilizumab (Actemra) could stabilize or improve lung function in people with early interstitial lung disease associated with systemic sclerosis (SSc-ILD), a new study...

Triplet Shows ‘Promising’ Activity in Unresectable/Metastatic CRC

Combining an EGFR inhibitor with a pair of checkpoint inhibitors can produce “promising” activity in certain patients with colorectal cancer (CRC), according to an investigator...

Feds Plead for Greater Use of Monoclonal Antibodies to Fight COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Federal officials are urging healthcare professionals and patients to use monoclonal...

We’re Getting Closer to a Lifesaving RSV Vaccine

Respiratory syncytial virus (RSV) vaccine development has progressed rapidly in recent years, and there is hope that an efficacious vaccine soon may be approved. Dr...

Experts Offer Roadmap for Treating CLL During the Pandemic

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. COVID-19 has thrown a wrench in standard treatment protocols for patients...

Type 1 Diabetes Screen Costing $55 Is Launched in US

A new initiative launched by the diabetes charity JDRF aims to broaden screening for type 1 diabetes risk for the general population of the United...

Ocular Side Effects Possible With Checkpoint Inhibitors

NEW YORK (Reuters Health) – People who use immune-checkpoint inhibitors have an increased risk of noninfectious uveitis and myasthenia gravis, according to a database study....

IDSA Updates COVID Guidelines for Antibodies, Antivirals, Others

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. An infectious disease expert panel cautions against routine use of bamlanivimab (Eli Lilly) and...

Tildrakizumab for Psoriasis Shows Durable Efficacy Over 5 Years

The full 5-year results of a long-term extension study of tildrakizumab for psoriasis show a high rate of sustained disease control coupled with a favorable safety...

Golimumab Preserves Insulin Production in Type 1 Diabetes

The human monoclonal antibody golimumab (Symponi) preserved endogenous insulin secretion in patients with new-onset type 1 diabetes and reduced their exogenous insulin requirements at 1...