Tag: manic depression

A Community-Based Mental Health Program Pivots During the Pandemic

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. For more than 70 years, Fountain House has offered a lifeline...

Low-Dose Nitrous Oxide Shows Benefit for Resistant Depression

A 1-hour treatment with a low concentration of nitrous oxide, commonly known as “laughing gas,” appears to relieve symptoms of treatment-resistant major depression (TRMD), with...

FDA Okays New Drug Option for Schizophrenia, Bipolar I Disorder

The US Food and Drug Administration (FDA) has approved a once-daily oral medication, which is a combination of olanzapine and samidorphan (Lybalvi, Alkermes), for the...

‘Calcium Imbalance’ Linked to Bipolar Severity

Calcium homeostasis may play a role in bipolar disorder (BD) severity, with raised serum vitamin D and parathyroid hormone (PTH) levels linked to worse clinical...

Novel Drug Offers Rapid Relief From Agitation in Serious Mental Illness

An investigational, orally dissolving film formulation of dexmedetomidine (BXCL501, BioXcel Therapeutics) may offer rapid relief from acute agitation related to schizophrenia or bipolar disorder (BD),...

Heart Rate Variability a Biomarker of Bipolar Disorder Severity?

Reduced heart rate variability (HRV) is associated with severity in patients with bipolar disorder (BD), in terms of both individual and overall measures of disease...

Adult Separation Anxiety Raises Suicidality Risk

Separation anxiety plays a substantial role in suicidality in patients with mood and anxiety disorders, new research suggests. Results of a study that included 500...

Billions of Years Old, Lithium Still Has a Promising Future

In a six-decade career spent researching and prescribing lithium ― a long-established therapy for bipolar disorder ― psychiatrist David Dunner, MD, has many stories about...

Lithium Resistance in Bipolar Tied to Deficient Gene Expression

A decrease in activation of a specific gene may explain why many patients with bipolar disorder (BD) do not respond to lithium, new research suggests....

Two Genes in Prefrontal Cortex Implicated in PTSD

NEW YORK (Reuters Health) – A post-mortem analysis of brain tissue from people diagnosed with post-traumatic stress disorder (PTSD) revealed that two genes in the...

Global Experts Map the Latest in Bipolar Management

A new monograph offers a far-reaching update on research and clinical management of bipolar disorders (BDs), including epidemiology, genetics, pathogenesis, psychosocial aspects, and current and...

Smartphone App Differentiates Bipolar Disorder, BPD

There’s a reason they’re called smartphones. Indeed, how patients use their smartphones and where they take them provides insight into what has been termed their...

Psilocybin Delivers ‘Remarkable’ Relief in Severe Depression

Psilocybin, the psychedelic compound in “magic mushrooms,” rapidly improves symptoms and produces remission in as little as two sessions for patients with major depression, new...

Add-On Psychotherapy a Win in Bipolar Disorder

Adding psychotherapy to pharmacotherapy benefits patients with bipolar disorder (BD), particularly when delivered in family or group settings, results of a new meta-analysis confirms. Outpatients...

Experts Call for Immediate Suspension of ECT, Others Push Back

Experts are calling for the immediate suspension of electroconvulsive therapy (ECT) for major depression. A new review by investigators led by John Read, PhD, University...

Caution Urged for Antidepressant Use in Bipolar Depression

Although patients with bipolar disorder commonly experience depressive symptoms, clinicians should be very cautious about treating them with antidepressants, especially as monotherapy, experts asserted in...

New Insight into Neurobehavioral Effects of Legalized Cannabis

Researchers have published one of the first studies to characterize the association between the consumption of legal cannabis and subsequent pharmacologic and neurobehavioral outcomes, with...

COVID-19 and Psychosis: Is There a Link?

Since the start of the COVID-19 pandemic, most of the research into the SARS-CoV-2 virus has focused on its direct effects on the body with...

Life in Jail Worse During COVID-19

What your doctor is reading on Medscape.com: APRIL 14, 2020 — Jails provide ideal conditions for the spread of COVID-19, as made clear by...