Tag: malignant neoplasia

Cancer Screening Stopped by Pandemic: Repercussions to Come?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Last year, cancer screening programs around the world ground to a...

Bariatric Surgery May Cut Cancer in Obesity With Liver Disease

In a large cohort of insured working adults with severe obesity and nonalcoholic fatty liver disease (NAFLD), among those who underwent bariatric surgery, the rate of...

Despite COVID, Americans Still Help Others With Medical Bills

The number of Americans donating to crowdfunding campaigns for medical bills during 2020 held steady relative to previous years, despite widespread financial hardships from the...

Patients With Cancer Need Both Doses of COVID Vax

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The first report on responses to COVID-19 vaccination among patients with...

Increase in Thyroid Cancer Rates Points to Overscreening

The incidence of thyroid cancer cases has increased markedly since the late 1990s, although rates vary widely between countries, and the increases have been largely...

No Benefit Seen With Everolimus in Early Breast Cancer

Adding everolimus to adjuvant hormone therapy for early ER+, HER2- breast cancer does not offer any benefit over hormone therapy alone, according to results of...

How Patients Decide on Surgery

Patients consider the risk of cancer and menopause, as well as other factors, when making decisions about ovarian cancer prevention surgery, according to a small...

Cancer Drugmaker Destroyed Records Before FDA Inspection

A company that manufacturer ingredients for cancer drugs used in the United States has pleaded guilty to concealing and destroying records prior to an inspection...

At-Home HPV Swab Tests for Cervical Screening in UK Trial

A trial of an at-home human papillomavirus (HPV) swab test has begun in London, United Kingdom, as part of an initiative to increase uptake of...

No Survival Benefit to Primary Resection Before Chemo in CRC

NEW YORK (Reuters Health) – Contrary to previous reports, primary tumor resection prior to chemotherapy did not confer a survival benefit in colorectal cancer patients...

US Cancer Drug Approvals Ensure Access but Not Value

Cancer drugs that have been approved in the United States are often not immediately approved in the United Kingdom and Canada, owing to uncertainty over...

FDA Places Clinical Hold on Sickle Cell Gene Therapy

The FDA placed a clinical hold yesterday on two gene therapy trials for sickle cell disease (SCD) after one participant developed acute myeloid leukemia (AML)...

Bladder Cancer Indication Withdrawn for Durvalumab

After failing to improve overall survival in unresectable metastatic bladder cancer in a phase 3 trial, this indication will be withdrawn in the United States...

CCR Score Can Guide Treatment After Radiation in Prostate Cancer

The combined clinical cell-cycle risk (CCR) score — derived from both clinical and genetic factors — can identify patients with intermediate- and high-risk localized prostate...

Liquid vs Tissue Biopsy in Prostate Cancer: Why Not Both?

The genomic landscape of circulating tumor DNA (ctDNA) was comparable to the landscape of tissue biopsies in a large study of patients with metastatic castration-resistant...

Does Cancer Care Inspire Great Writing?

Oncologists face unique emotional challenges because of the frequency of the morbidity and mortality they see, which may be unparalleled among specialists. “We see tragedy...

Amivantamab Shows Promise in Challenging EGFR-Mutated NSCLC

A novel drug, the immune cell-directing antibody amivantamab (under development by Janssen), has shown promise for the treatment of patients with non–small cell lung cancer...

Genetic Deletions Drive SARS-CoV-2 Antibody ‘Escape’

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Recurrent genetic deletions in the SARS-CoV-2 spike protein can change the...

Tofacitinib Linked to Risk for Cardiac Events, Cancer, FDA Warns

The Food and Drug Administration has alerted the public to an increased risk of serious heart-related problems and cancer risk associated with the Janus kinase...

MRI-Guided Prostate Biopsy Prevails in PRECISE Trial

Here’s welcome news for men of a certain age: new results support a less invasive approach to investigations for suspicion of prostate cancer. An approach...

Which Patients With Kidney Cancer Are Likely to Respond to ICI?

Several factors associated with a diminished response to immune checkpoint inhibitor (ICI) drugs among patients with metastatic clear cell renal cell carcinoma (ccRCC) have been...

Fecal Transplant Overcomes Resistance to Immunotherapy

For some patients with advanced melanoma whose conditions had stopped responding to immunotherapy, response was restored after treatment with fecal transplants. The material for the...

Tofacitinib for RA Misses the Mark in Safety Study

Daily treatment with tofacitinib (Xeljanz) led to more malignancies and adverse cardiovascular events in older rheumatoid arthritis patients compared with treatment with a tumor necrosis...

Liquid Biopsies Helpful in Prostate Cancer, but Most Not Ready for Routine Use

NEW YORK (Reuters Health) – Liquid biopsies have the potential to guide therapeutic decision making in prostate cancer, but issues such as assay standardization, cost...

Obesity ‘Clearly’ Not Tied to Worse Survival in MBC

The relationship between obesity and overweight and breast cancer has some elements of mystery. But this is not one of them: in metastatic breast cancer...