Tag: major depression

Cannabis Use Tied to Increased Risk for Suicidal Thoughts, Actions

Young adults who use cannabis ― either sporadically, daily, or those who have cannabis use disorder ― have a significantly increased risk for suicidal thoughts...

Key Driver of Fish Oil’s Antidepressant Effects Revealed

A key molecular mechanism underpinning the anti-inflammatory, antidepressant, and neuroprotective effects of omega-3 fatty acids has been identified.   In findings that could lead to...

A Community-Based Mental Health Program Pivots During the Pandemic

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. For more than 70 years, Fountain House has offered a lifeline...

Low-Dose Nitrous Oxide Shows Benefit for Resistant Depression

A 1-hour treatment with a low concentration of nitrous oxide, commonly known as “laughing gas,” appears to relieve symptoms of treatment-resistant major depression (TRMD), with...

Can a Routine Cancer Scan Flag Depression?

Whole-body imaging that is performed routinely in the treatment of patients with multiple myeloma could offer the added benefit of flagging those with possible depression,...

Psychiatric Fallout From Long-COVID: How to Prepare

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. As mounting evidence points to a significant psychiatric component of COVID-19,...

Heart Rate Variability a Biomarker of Bipolar Disorder Severity?

Reduced heart rate variability (HRV) is associated with severity in patients with bipolar disorder (BD), in terms of both individual and overall measures of disease...

Psilocybin Matches SSRI for Moderate-to-Severe Depression

The psychedelic drug psilocybin performed just as well as a widely used antidepressant in easing the symptoms of major depression, and outperformed the selective serotonin...

Adult Separation Anxiety Raises Suicidality Risk

Separation anxiety plays a substantial role in suicidality in patients with mood and anxiety disorders, new research suggests. Results of a study that included 500...

Novel Therapeutic Target for Depression Identified

An anti-seizure medication appears to reduce anhedonia in patients with depression via a novel mechanism that may offer a new therapeutic target for the disorder,...

Do Antidepressants Increase Risk of Brain Bleeds?

Contrary to previous findings, selective serotonin reuptake inhibitors (SSRI) are not associated with an increased risk of intracerebral hemorrhage (ICH), results of a large observational...

Depression, Chronic Comorbidities ‘Inextricably Linked’

For many adults, depression and chronic medical conditions are inextricably linked. In fact, the prevalence of depression is 2-10 times higher among people with chronic...

Higher Dietary Fiber Tied to Lower Depression Risk in Young Women

Higher fiber intake may be associated with decreased risk of depression in premenopausal women, new research suggests. Investigators analyzed data from close to 6000 pre-...

Global Experts Map the Latest in Bipolar Management

A new monograph offers a far-reaching update on research and clinical management of bipolar disorders (BDs), including epidemiology, genetics, pathogenesis, psychosocial aspects, and current and...

Three Key Factors Tied to Higher Suicide Risk in BPD

Three specific symptoms may help clinicians identify patients with borderline personality disorders (BPD) at highest risk for suicide. Results of a large longitudinal study show...

New Risks of Prescription Opioids Discovered

Prescription opioid use increases the risk for major depressive disorder (MDD) and anxiety and stress-related disorders (ASRD), new genetic evidence shows. The findings also suggest...

Psilocybin Delivers ‘Remarkable’ Relief in Severe Depression

Psilocybin, the psychedelic compound in “magic mushrooms,” rapidly improves symptoms and produces remission in as little as two sessions for patients with major depression, new...

Irritability in ADHD May Flag Suicide Risk

Irritability appears to be a potent independent predictor of increased risk for suicidality in children and adolescents with ADHD, Tomer Levy, MD, said at the...

Depression or Anxiety? Blood Biomarkers May Tell the Tale

Metabolic alterations linked to inflammation and lipid metabolism can distinguish depression from anxiety and determine disease severity, new research suggests.  Results from a Dutch study...

Breathing Enriched Oxygen May Improve Major Depression

Breathing enriched oxygen on a nightly basis may lead to clinically meaningful symptomatic improvement in mild to moderate major depression, new research suggests. Dr R....

ECG Promising for Predicting Major Depression, Treatment Response

Individuals with major depressive disorder (MDD) have an increased heart rate — a finding that may have the potential to identify individuals at risk for...

Frequent Cannabis Use in Depression Tripled Over Past Decade

Not only are individuals with depression at significantly higher risk for cannabis use compared with those without depression, this trend has increased dramatically over the...

Experts Call for Immediate Suspension of ECT, Others Push Back

Experts are calling for the immediate suspension of electroconvulsive therapy (ECT) for major depression. A new review by investigators led by John Read, PhD, University...

ECT More Effective for Psychotic vs Nonpsychotic Depression?

For patients with psychotic depression, response to treatment, remission rates, and cognitive improvement are better following electroconvulsive therapy (ECT) than for patients with nonpsychotic depression,...

Caution Urged for Antidepressant Use in Bipolar Depression

Although patients with bipolar disorder commonly experience depressive symptoms, clinicians should be very cautious about treating them with antidepressants, especially as monotherapy, experts asserted in...