Tag: lipids

Hepatotoxicity Risk Differs Between Psoriasis, PsA, and RA Patients

Patients taking methotrexate for psoriasis or psoriatic arthritis (PsA) were at a higher risk of developing liver disease than were patients with rheumatoid arthritis (RA)...

In Transgender Youth, Obesity Impacts Effects of Sex Steroids on HDL-C

NEW YORK (Reuters Health) – In transgender and gender-diverse young people receiving sex steroids, obesity exacerbates the decrease in high-density lipoprotein cholesterol (HDL-C) levels and...

Cardiometabolic Subspecialty Is ‘One-Stop Shop’ Approach to Diabetes

A one-stop shop approach to managing the spectrum of complications in patients with type 2 diabetes with a coordinated, multidisciplinary team of clinicians has taken...

Sickle-Cell Trait May Not Independently Elevate CHD Risk

African Americans with sickle-cell trait (SCT), that is, who are heterozygous for the sickle-cell gene variant, don’t as a result necessarily have an elevated risk...

Lp(a) and LPA Gene Score ‘Modest’ Predictors of CVD Risk

Although lipoprotein(a) (Lpa) levels and LPA genetic risk scores are both significantly associated with atherosclerotic cardiovascular disease (ASCVD) events, they appear to offer only a...

Ultraprocessed Food Again Linked to Increased CVD, Death

Yet another study has linked the consumption of ultraprocessed, or “junk,” foods to bad health outcomes. In a longitudinal analysis of more than 22,000 men...

Novartis Receives FDA Complete Response Letter on Inclisiran

The US Food and Drug Administration (FDA) issued a complete response letter regarding Novartis’ new drug application (NDA) for inclisiran, a novel treatment for elevated...

LDL Not the Primary Culprit in ASCVD?

Two new studies suggest that low-density lipoprotein cholesterol (LDL-C) may be not the main driver of atherosclerotic cardiovascular disease (ASCVD). The findings instead implicate remnant...

Peripheral Neuropathy Tied to Mortality in Adults Without Diabetes

Peripheral neuropathy is common in US adults and is associated with an increased risk of death, even in the absence of diabetes, researchers report today...

PFO Closure Beneficial in Stroke Patients With Thrombophilia

Thrombophilic patients who have had an ischemic stroke and have a patent foramen ovale (PFO) benefit from having the PFO closed, a new study suggests....

Sedentary Postmenopausal Women Have Higher HF Risk

The more time older women spent sitting or lying down, the more likely their risk of hospitalization for heart failure, based on data from more...

USPSTF Continues to Back Behavioral Intervention to Cut CVD Risk

Adults with risk factors for cardiovascular disease (CVD) should be offered or referred for behavioral counseling to promote a healthy diet and physical activity, the...

Chili Pepper Consumption Linked to Better Midlife Survival

In a meta-analysis of four geographically diverse observational studies, a higher intake of any type of chili pepper was associated with a lower rate of...

Remote, Non-Physician-Led Care Cuts LDL, BP in High-Risk Patients

A novel algorithm-based disease management program, led by pharmacists and nonlicensed navigators, optimized cholesterol and blood pressure levels in high-risk patients, according to an interim...

Statins Beneficial in Elderly, Guidelines Should Be Strengthened

Contrary to historical evidence, among older people, elevated LDL cholesterol levels increase risk for heart attack and cardiovascular disease, and older patients benefit as much,...

No Secondary Prevention Benefit With Omega-3s in Elderly

Omega-3 fatty acids on top of standard care did not reduce major cardiovascular events or death in elderly survivors of an acute myocardial infarction (MI)...

SAMSON Pins Most Muscle Pain With Statins on the Nocebo Effect

A novel randomized trial taking on a vexing issue around one of the world’s most commonly prescribed medications has concluded that frequently intolerable statin side...

STRENGTH Trial Questions CV Benefit of High-Dose Omega-3s

Questions about the cardiovascular benefit of omega-3 fatty acids and the high-dose eicosapentaenoic acid (EPA) product, icosapent ethyl (Vascepa, Amarin), have resurfaced with the presentation...

Polypill Provides Meaningful Primary CV Prevention

A once-daily polypill containing four drugs to lower blood pressure and LDL cholesterol reduced major adverse cardiovascular events by 21% relative to placebo in people...

Clopidogrel Bests Ticagrelor for Elective PCI

Ticagrelor failed to unseat clopidogrel as the guideline-recommended P2Y12 inhibitor of choice in patients undergoing elective percutaneous coronary intervention for stable CAD in the randomized...

Simple Questionnaire Can Identify Silent Atherosclerosis

Individuals in the general population with high levels of silent coronary atherosclerosis can be successfully identified with a simple questionnaire that they can complete themselves...

Omega-3, Vit-D Both Fail at AF Primary Prevention in VITAL-Rhythm

Clinical trials of omega-3 fatty acid or vitamin D supplements have followed a long and winding road in search of benefits in cardiovascular (CV) disease,...

Vascular Comorbidity in MS Linked to Atrophy, Functional Decline

Vascular comorbidities, including diabetes and hypertension, are linked to significantly lower measures of neurologic function in people with multiple sclerosis (MS) vs patients without these...

Data Contradict on Statin Effect in Diabetes With COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Two observational studies have yielded opposite findings regarding the effect of...

Higher Serum Omega-3 Tied to Better Outcome After STEMI

Regular consumption of foods rich in omega-3 fatty acids was associated with improved prognosis after ST-segment myocardial infarction (STEMI) in a new observational study. The...