Tag: lipids

No Overall Statin Effect Seen on Dementia, Cognition

Statin therapy likely didn’t lead to dementia or even mild cognitive impairment (MCI) in older patients taking the drugs for cardiovascular (CV) primary prevention in...

A1c Below Prediabetes Cutoff Linked to Subclinical Atherosclerosis

Hemoglobin A1c above 5% but below the prediabetes cutoff of 5.5% is an additional potential biomarker of subclinical atherosclerosis in people with low cardiovascular disease...

LDCT Lung Cancer Screening May ID Aortic Stenosis Risk

Using low-dose computed tomography (LDCT) to screen for aortic valve calcification during a lung cancer screening could identify those at risk for aortic stenosis, says...

Lipoprotein Apheresis Shows Durable Impact on CV Outcomes

Lipoprotein apheresis (LA) is a safe and effective treatment for very-high-risk dyslipidemia, sustainably reducing cholesterol and lipoprotein levels to within target levels and markedly lowering...

Aerobic Training Boosts the Power of Antihypertensive Drugs

Aerobic exercise augments the blood pressure-lowering effect of antihypertensive medication in hypertensive individuals with metabolic syndrome. In a small study, these patients experienced a greater...

Genotype-Guided Antiplatelet Therapy Misses Mark

The observational extended study of the previously reported 12-month randomized TAILOR-PCI trial shows genotype-guided antiplatelet therapy after percutaneous coronary intervention (PCI) did not significantly reduce...

Do Anti-ApoA-1 Antibodies Link Fatty Liver Disease and CVD?

Anti-apolipoprotein A-1 (ApoA-1) antibodies are common in non-alcoholic fatty liver disease (NAFLD) and may not only drive its development but also underlie the link between...

Limited-Variant Screening Tests Often Miss Familial Hypercholesterolemia

NEW YORK (Reuters Health) – Two-thirds of cases of familial hypercholesterolemia (FH) would be missed by relying on array-based genetic tests that screen for only...

BP Lowering Useful in CV Risk Management Even at Normal Levels

Lowering blood pressure with antihypertensive medication protects against future cardiovascular (CV) events even in people with normal or only mildly elevated blood pressure, a large...

New AHA Guidance on Obesity and Cardiovascular Risk

An updated American Heart Association scientific statement on the role of obesity in cardiovascular disease provides the first new guidance in 15 years, drawing on...

Arthritis Drug May Curb Myocardial Damage in Acute STEMI

Early use of tocilizumab (Actemra) does not reduce myocardial infarct size but modestly increases myocardial salvage in patients with acute ST-segment elevation myocardial infarction (STEMI),...

OCS Heart System Earns Hard-Won Backing of FDA Panel

After more than 10 hours of intense debate, a US Food and Drug Administration (FDA) advisory panel gave its support to a premarket approval application...

Vasodilatory Medications Found Protective Against Rosacea

Vasodilators may have a protective effect against rosacea, results from a single-center retrospective cohort study showed. “Our initial hypothesis was that perhaps antihypertensive agents might...

Eating Fish Links With Fewer CVD Events in High-Risk People

People with cardiovascular disease (CVD) who regularly ate fish had significantly fewer major CVD events and there were fewer total deaths compared with similar individuals...

Hepatotoxicity Risk Differs Between Psoriasis, PsA, and RA Patients

Patients taking methotrexate for psoriasis or psoriatic arthritis (PsA) were at a higher risk of developing liver disease than were patients with rheumatoid arthritis (RA)...

In Transgender Youth, Obesity Impacts Effects of Sex Steroids on HDL-C

NEW YORK (Reuters Health) – In transgender and gender-diverse young people receiving sex steroids, obesity exacerbates the decrease in high-density lipoprotein cholesterol (HDL-C) levels and...

Cardiometabolic Subspecialty Is ‘One-Stop Shop’ Approach to Diabetes

A one-stop shop approach to managing the spectrum of complications in patients with type 2 diabetes with a coordinated, multidisciplinary team of clinicians has taken...

Sickle-Cell Trait May Not Independently Elevate CHD Risk

African Americans with sickle-cell trait (SCT), that is, who are heterozygous for the sickle-cell gene variant, don’t as a result necessarily have an elevated risk...

Lp(a) and LPA Gene Score ‘Modest’ Predictors of CVD Risk

Although lipoprotein(a) (Lpa) levels and LPA genetic risk scores are both significantly associated with atherosclerotic cardiovascular disease (ASCVD) events, they appear to offer only a...

Ultraprocessed Food Again Linked to Increased CVD, Death

Yet another study has linked the consumption of ultraprocessed, or “junk,” foods to bad health outcomes. In a longitudinal analysis of more than 22,000 men...

Novartis Receives FDA Complete Response Letter on Inclisiran

The US Food and Drug Administration (FDA) issued a complete response letter regarding Novartis’ new drug application (NDA) for inclisiran, a novel treatment for elevated...

LDL Not the Primary Culprit in ASCVD?

Two new studies suggest that low-density lipoprotein cholesterol (LDL-C) may be not the main driver of atherosclerotic cardiovascular disease (ASCVD). The findings instead implicate remnant...

Peripheral Neuropathy Tied to Mortality in Adults Without Diabetes

Peripheral neuropathy is common in US adults and is associated with an increased risk of death, even in the absence of diabetes, researchers report today...

PFO Closure Beneficial in Stroke Patients With Thrombophilia

Thrombophilic patients who have had an ischemic stroke and have a patent foramen ovale (PFO) benefit from having the PFO closed, a new study suggests....

Sedentary Postmenopausal Women Have Higher HF Risk

The more time older women spent sitting or lying down, the more likely their risk of hospitalization for heart failure, based on data from more...