Tag: hormone therapy

IL-6 Levels Predict Distant Breast Cancer Recurrence

The inflammatory cytokine interleukin 6 may be a biomarker for distant recurrence of breast cancer among patients treated for stage II-III HER2-negative disease, investigators have...

Pandemic Leads Doctors to Rethink Unnecessary Treatment

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Covid-19 is opening the door for researchers to address a problem...

Chemoimmunotherapy in Invasive Lobular Breast Cancer

The PD-L1 inhibitor atezolizumab (Tecentriq) combined with carboplatin has shown signs of clinical activity in women with metastatic invasive lobular breast cancer (ILC) according to...

Quicker Fertility Rebound in Young Women With Breast Cancer

For a young woman diagnosed with breast cancer, the prospect that the treatment needed for the cancer may irreversibly impair fertility piles on distress. A...

Progesterone Effective in Speeding Recovery From TBI?

Progesterone may have a protective effect against the impact of mild traumatic brain injury (mTBI) in female athletes when the injury takes place during the...

No Benefit Seen With Everolimus in Early Breast Cancer

Adding everolimus to adjuvant hormone therapy for early ER+, HER2- breast cancer does not offer any benefit over hormone therapy alone, according to results of...

Large Study Finds Trans Men on Testosterone at Risk for Blood Clots

Over 10% of transgender men (females transitioning to male) who take testosterone develop high hematocrit levels that could put them at greater risk for a...

CCR Score Can Guide Treatment After Radiation in Prostate Cancer

The combined clinical cell-cycle risk (CCR) score — derived from both clinical and genetic factors — can identify patients with intermediate- and high-risk localized prostate...

Increased Risk of Meningioma With Cyproterone Acetate Use

New details confirm an increased risk of developing intracranial meningiomas after prolonged use of the hormonal product cyproterone acetate. Cyproterone acetate is a synthetic progestogen...

First Mammography Guidelines for Older Breast Cancer Survivors

The first guidelines ever released for screening mammography for older survivors of breast cancer (>75 years) recommend that routine mammography be discontinued for women whose...

Adding Liothyronine for Hypothyroidism Doesn’t Up Breast Cancer Risk

The combination of liothyronine (LT3) with levothyroxine (LT4) for the treatment of hypothyroidism shows no evidence of any increased risk of breast cancer in a...

No Need to Stop Estrogen in Transgender Women Before Gender-Affirming Surgery

NEW YORK (Reuters Health) – Transgender women can safely maintain their estrogen hormone therapy during gender-affirming surgery without an increased risk of venous thromboembolism (VTE),...

Entinostat Doesn’t Overcome Endocrine Resistance in Breast Cancer

The histone deacetylase (HDAC) inhibitor entinostat failed to overcome resistance to endocrine therapy in hormone receptor–positive, HER2-negative, advanced breast cancer in a phase 3 trial....

Even More Women May Forgo Chemo for Breast Cancer

More women with early-stage breast cancer may safely forgo chemotherapy, suggests an interim analysis that had a median follow-up of 5 years of the large-scale...

Breast Cancer Facts Doctors Might Not Tell You

Florida real estate agent Sondra Burwick learned in 1996 that she had ductal carcinoma in situ (DCIS) in her right breast. DCIS, also called stage...

Palbociclib Disappoints in HR+, HER2– Breast Cancer

The CDK4/6 inhibitor palbociclib provides no significant benefit in patients with hormone receptor–positive (HR+), HER2-negative primary breast cancer, according to first results from the PENELOPE-B...

What’s Hot, Including a Major Chemotherapy Trial

The “hottest” presentation at the upcoming 2020 San Antonio Breast Cancer Symposium (SABCS) comes from RxPONDER (abstract GS3-00), a major randomized clinical trial assessing use...

Transgender Cancer Patients May Not Realize Treatment Can Interact With Their Hormone Therapy

NEW YORK (Reuters Health) – Transgender cancer patients often were not told of potential interactions between cancer treatment and gender-affirming hormone therapy, a case series...

Genitourinary Syndrome of Menopause Statement Stresses Tx Options

It’s important for clinicians to ask women whether they are experiencing symptoms of genitourinary syndrome of menopause (GSM) before and after menopause, according to a...

New Nonhormonal Hot Flash Treatments on the Way

A new group of nonhormonal drugs currently in clinical trials shows strong promise for treating menopausal hot flashes as effectively as hormones, researchers told attendees...

Hold Off Radiotherapy After Prostate Cancer Surgery

Most men who undergo radical prostatectomy can skip adjuvant radiotherapy and can be followed with observation alone. They can undergo early salvage radiotherapy if the...

Dermatologists’ Key Role in Transforming Transgender Patients

Whether they realize it or not, dermatologists play a key role in the physical transformation of transgender patients, according to Doris Day, MD. While clinical management...

Cognitive Decline With Endocrine Tx for Breast Ca

Cognitive impairment seen in women with early breast cancer who undergo chemotherapy ― so-called chemobrain ― has now been reported in patients who are treated...

COVID-19 Breast Cancer Patient Triage Guidelines (CPBCC)

What your doctor is reading on Medscape.com: APRIL 08, 2020 — The guideline on COVID-19–related triage of patients with breast cancer was released on...

Does Thyroid Hormone Therapy in Older Age Increase Risk of Death?

Older adults with isolated elevations in thyroid-stimulating hormone (TSH) who are treated with thyroid replacement therapy show an increased risk of death relative to the...