Tag: hiv infection

Cryptococcal Meningitis: Single-Dose Regimen Noninferior

A single high dose of the antifungal agent liposomal amphotericin B (L-AmB; AmBisome, Gilead Sciences), with a background regimen of flucytosine and fluconazole, is noninferior...

HIV Acquisition on PrEP Rare, With Some Drug Resistance

Out of an estimated 104,000 people offered HIV preexposure prophylaxis (PrEP) to protect themselves from HIV, just 14 people acquired a strain of HIV resistant...

Failed viral suppression in CAB/RPV linked to 3 Risk Factors

A body mass index (BMI) ≥30 kg/m2, rilpivirine resistance–associated mutations, and the HIV-1 subtype A6/A1 can raise a person’s risk for confirmed virologic failure (CVF)...

Younger Adults With HIV Have Higher CVD Risk but Low ASCVD Scores

People age 40 and younger living with HIV have a higher risk for heart disease than even their over-40 peers living with HIV — and...

Dolutegravir Confirmed as Effective Second-Line HIV Therapy

Dolutegravir and ritonavir-boosted darunavir are equally effective second-line treatments for HIV-1, even for patients with resistance to nucleoside reverse-transcriptase inhibitors (NRTIs) in the regimen, a...

Monkeys May Lead the Way for Immunotherapy HIV Cure

A small study conducted in rhesus macaques found a 10-fold reduction in HIV viral load when the monkeys received immunotherapy to block programmed cell death...

Lenacapavir Shows Viral Suppression in Drug-Resistant HIV

Dr Jean-Michel Molina The long-acting drug lenacapavir, a first-in-class capsid inhibitor, shows sustained viral suppression in a small cohort of heavily treatment-experienced patients with multidrug-resistant...

HIV Increases Risk for Severe COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. HIV increases the risk for severe COVID-19 by 6% and the...

Adjustments to BPaL Regimen Reduce AEs, Not Efficacy

Lower doses of linezolid in the BPaL drug regimen (bedaquiline, pretomanid, and linezolid) significantly reduce the adverse events associated with the treatment for patients with highly...

Moving Forward With HIV Care, Cure, and PrEP

The COVID-19 pandemic has overshadowed innovations in HIV care and prevention, says Tonia Poteat, PhD, MPH, PA-C, a primary HIV care and HIV preexposure prophylaxis...

Cardiology Journal Flags Papers Cited Hundreds of Times

A European cardiology journal has issued expressions of concern for seven widely-cited papers dating back to 2009 after a reader flagged suspicious images in the...

Limited English Proficiency Linked With Less Healthcare

Adults with limited English skills receive far less health care than do those proficient in English, according to a new study in Health Affairs. Jessica...

Highly Respected, Beloved Pediatric Neurologist Dies

Verne Strudwick Caviness, Jr, MD, PhD, a highly respected pediatric neurologist and researcher, died at his home in Rockport, Massachusetts, on July 6. He was...

Tislelizumab Benefit in HCC Undimmed by Prior Therapies

With the novel immunotherapy tislelizumab, durable responses are achieved for patients with advanced hepatocellular carcinoma (HCC), regardless of the number of prior lines of therapy,...

Prominent Nephrologist, Mount Sinai Chair of Medicine Dies

Dr Barbara T. Murphy Barbara T. Murphy, MD, renowned nephrologist and professor of medicine at Mount Sinai School of Medicine in New York City, has...

Hospital Prices Must Now Be Transparent for Consumers

A colonoscopy might cost you or your insurer a few hundred dollars — or several thousand, depending on which hospital or insurer you use. Long...

Walking Speed Following Stroke a Good Predictor of Recovery?

Walking speed after stroke may help predict which patients will show greater post-rehab improvement in their ability to simultaneously walk and perform a second task,...

Should Feds Allow a Therapy That Pays Meth Users to Abstain?

In his multiple attempts to overcome a methamphetamine addiction that ground through two decades of his life, Tyrone Clifford Jr. remembers well the closest he...

Heartburn Drugs Improve Blood Sugar Control in Diabetes

WASHINGTON—Antacids improved blood sugar control in people with diabetes but had no effect on reducing the risk of diabetes in the general population, according to...

The Pandemic Hurt Patients With Liver Disease in Many Ways

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The COVID-19 pandemic has worsened the health of patients with liver...

Probiotic Supplementation Regulates Newborn Immune System

Supplementing breastfed infants with bifidobacteria promotes development of a well-regulated immune system, theoretically reducing risk of immune-mediated conditions like allergies and asthma, according to investigators....

Is HIV Criminalization the No. 1 Barrier to Ending the Epidemic?

For many people, being told that they are HIV positive is no longer a death sentence. But for Robert Suttle, a Black gay man and...

Liver Transplant Outcomes Improving for US Patients With HIV/HCV

While liver transplant outcomes were historically poor in people coinfected with HIV and hepatitis C virus (HCV), they have improved significantly in the era of...

Jack Remington, MD, Noted Toxoplasmosis Researcher, Dies at 90

Dr Jack. S. Remington Jack. S. Remington, MD, the Stanford University clinical scientist who developed a test to identify babies at risk for dangerous toxoplasmosis,...

Treatment Paradigm for Chronic HBV in Flux

These days deciding when to stop targeted treatment for chronic hepatitis B is a bigger challenge than knowing when to start, Norah A. Terrault, MD,...