Tag: hemorrhage

Ticagrelor Beneficial for Moderate Stroke: New THALES Analysis

For patients with a moderate-size stroke, benefit from ticagrelor plus aspirin was the same as for patients with minor stroke, a new exploratory analysis of...

‘Trauma Centers’ Huge Fees to Treat Minor Injuries and Send Home

The care was ordinary. A hospital in Modesto, California, treated a 30-year-old man for shoulder and back pain after a car accident. He went home...

Novel Liver Dialysis Device May Safely Curb ACLF

An investigational liver dialysis device (DIALIVE) was associated with significantly greater survival of patients with acute-on-chronic liver failure (ACLF), compared with the standard of care...

Thermal Ablation May Reduce Residual, Recurrent Adenomas

Thermal ablation of the defect margin after endoscopic mucosal resection (EMR-T) is associated with reduced recurrence in the treatment of large (≥20-mm) nonpedunculated colorectal polyps...

Zanubrutinib Better Than Ibrutinib in CLL/SLL?

Zanubrutinib (Brukinsa), a second-generation Bruton tyrosine kinase (BTK) inhibitor, has shown a significantly greater delay in disease progression vs the standard of care ibrutinib (Imbruvica)...

Genotype-Guided Antiplatelet Therapy Misses Mark

The observational extended study of the previously reported 12-month randomized TAILOR-PCI trial shows genotype-guided antiplatelet therapy after percutaneous coronary intervention (PCI) did not significantly reduce...

‘Hidden Tongue-Ties’ in Infants Have Scant Scientific Backing

When Amanda Green had a baby in 2015, she had no idea how hard it would be to feed him. After struggling to breastfeed for...

Ublituximab Plus Ibrutinib for CLL

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease associated with several known genetic abnormalities, including 17p deletion (del[17p]), 11q deletion (del[11q]), and TP53 gene...

Do Antidepressants Increase Risk of Brain Bleeds?

Contrary to previous findings, selective serotonin reuptake inhibitors (SSRI) are not associated with an increased risk of intracerebral hemorrhage (ICH), results of a large observational...

No Survival Benefit to Primary Resection Before Chemo in CRC

NEW YORK (Reuters Health) – Contrary to previous reports, primary tumor resection prior to chemotherapy did not confer a survival benefit in colorectal cancer patients...

Radial-to-Backup Artery Switch Adds Limited Risk in ACS PCI

There’s a price to pay for a failed radial artery attempt in invasively managed patients with acute coronary syndrome (ACS), but it may not be...

Ultra-Early Tranexamic Acid of No Benefit for Subarachnoid Hemorrhage

NEW YORK (Reuters Health) – In patients with subarachnoid hemorrhage due to a ruptured aneurysm, ultra-early, short-term tranexamic acid (TXA) did not improve clinical outcomes...

Score Aids Treatment Decision in Mild Large-Vessel Stroke

Patents who experience an ischemic stroke and who have a large-vessel occlusion but only mild symptoms are at “substantial” risk for early neurologic deterioration after...

Surgery Equals Drug Tx for Bleeding in Diabetic Retinopathy

In the treatment of vitreous hemorrhage from proliferative diabetic retinopathy, intraocular injection with anti–vascular endothelial growth factor (VEGF) shows similar efficacy to that of vitrectomy...

No Benefit From Tranexamic Acid Prophylaxis in Blood Cancers

Despite being routinely used in clinical settings, prophylactic use of tranexamic acid, an antifibrinolytic agent administered with platelet transfusions, did not reduce bleeding among patients...

Rivaroxaban Rivals Warfarin in AF, Mitral Bioprosthesis

The direct oral anticoagulants (DOACs) took cardiology by storm a decade ago when trials showed they were at least as safe and effective as warfarin...

Clopidogrel Bests Ticagrelor for Elective PCI

Ticagrelor failed to unseat clopidogrel as the guideline-recommended P2Y12 inhibitor of choice in patients undergoing elective percutaneous coronary intervention for stable CAD in the randomized...

Iatrogenic Injury During Cervical Cancer Screening

Cervical cancer screening is a routine procedure, but in rare instances, there can be medical complications. A new study finds that, compared to women who...

Post-Dental Extraction Bleeding Decreases With Mouth Splints

Dental extractions can cause significant risk of bleeding in hemophilia patients being treated with factor replacements. However, mouth splints significantly decreased the risk of postextraction...

Relugolix Combo Effective for Uterine Fibroids Through 1 Year

A combination therapy using the experimental drug relugolix was effective in treating pain and heavy bleeding from uterine fibroids for a full year, according to...

Intensive Blood Pressure Lowering Potentially Harmful in ICH

Intensive lowering of systolic blood pressure (SBP) for patients with intracerebral hemorrhage (ICH) whose initial SBP is excessively high does not improve outcomes and is...

‘Cautious’ DOAC Underdosing in AF May Push Mortality Higher

The risk for death goes up for patients with atrial fibrillation (AF) who are put on direct oral anticoagulants (DOAC) at dosages other than those...

REALITY Trial Supports Restrictive Transfusion in Anemic MI

A restrictive blood transfusion strategy in myocardial infarction patients with anemia proved safe, significantly less costly, and at least as effective as the standard liberal...

Mini-Dose Edoxaban May Safely Cut AF Stroke Risk in Very Elderly

An ultra-low dose of direct oral anticoagulant (DOAC) may safely cut the risk for stroke in very elderly patients with atrial fibrillation (AF) whose bleeding...

New ESC/EACTS Guideline on Atrial Fibrillation

New atrial fibrillation management guidelines from the European Society of Cardiology (ESC) call for diagnostic confirmation and structured characterization of AF and the need to...