Tag: hematology

Infusion Centers May Best EDs for Treating Sickle Cell Crises

Adults with sickle cell disease who experienced a vaso-occlusive crisis had substantially better outcomes when they were treated at specialty infusion centers than those treated...

FDA Approves New Asparaginase Product for Leukemia

The US Food and Drug Administration (FDA) has approved a new version of asparaginase for use in children and adults who have developed hypersensitivity to...

Thrombosis With Thrombocytopenia After mRNA COVID-19 Vaccine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. What is believed to be the first case of thrombosis with...

Hypomethylating Agents in Children With Relapsed/Refractory AML

Hypomethylating agents are generally considered to be agents of choice for older adults with acute myeloid leukemia who cannot tolerate the rigors of more intensive...

COVID-19 Vaccines Safe, Effective for Patients With Migraine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It is safe for patients with migraine to receive any of...

Reduced-Intensity Transplant Benefits Older Patients With AML

Among older patients with acute myeloid leukemia (AML), survival is significantly better when they undergo reduced-intensity condition (RIC) before receiving an allogeneic hematopoietic cell transplant...

Zanubrutinib Better Than Ibrutinib in CLL/SLL?

Zanubrutinib (Brukinsa), a second-generation Bruton tyrosine kinase (BTK) inhibitor, has shown a significantly greater delay in disease progression vs the standard of care ibrutinib (Imbruvica)...

Luspatercept Benefit Also in Non-Transfusion-Dependent Thalassemia

The first-in-class erythroid maturation agent luspatercept (Reblozyl) is already approved for the treatment of anemia in adult patients with beta thalassemia who require red blood...

One Quarter of 30–49-Year-Olds Have Abnormal Colonoscopy Results

More than one quarter of colonoscopies carried out in Americans aged 30 to 49 years reveal some type of neoplasm, and slightly over 6% of...

Can a Routine Cancer Scan Flag Depression?

Whole-body imaging that is performed routinely in the treatment of patients with multiple myeloma could offer the added benefit of flagging those with possible depression,...

Sex Differences in Pediatric B-ALL Outcomes Persist

Even in the age of intensive therapy and extensive risk stratification, there are small but significant differences in outcomes between boys and girls with B-lineage...

Mother-to-Infant COVID-19 Transmission Is Unlikely

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Mothers exposed to COVID-19 during pregnancy are not likely to transmit...

Blood Test for 50 Cancers Coming to US Clinics Soon

The novel Galleri blood test (GRAIL, Inc.), which claims to detect up to 50 different cancers from single blood draw, is about to make its...

JAMA Publishes Trial Results Delayed 5 Years. Here’s Why

A treatment for shortening the painful episodes of sickle cell disease (SCD) is not effective, results published in JAMA indicate. But the effort it took...

Ublituximab Plus Ibrutinib for CLL

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease associated with several known genetic abnormalities, including 17p deletion (del[17p]), 11q deletion (del[11q]), and TP53 gene...

Researchers Detail More Cases of Clots Tied to COVID Vaccines

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. New evidence emerged today tying vaccines for COVID-19 to extremely rare...

Made-to-Order TILs Effective Against Metastatic Melanoma

In just over one third of patients with metastatic melanoma who had experienced disease progression while receiving multiple prior lines of therapy, including immunotherapy and...

CDC Panel Leaves J&J Pause in Place for at Least a Week

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Center for Disease Control and Prevention’s (CDC’s) Advisory Committee on...

J&J Pause Magnifies Worry About COVID-19 Vaccine Hesitancy

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. The news today that states are being asked to pause administration...

How to Counsel Worried Patients About the J&J Vaccine News

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Dr Jan E. Patterson On April 13, the CDC and the...

Cancer Screening Stopped by Pandemic: Repercussions to Come?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Last year, cancer screening programs around the world ground to a...

Steroids Can Be Stopped in Some Older Myeloma Patients

For select older patients, it is safe to switch to a lower dose of lenalidomide maintenance therapy and discontinue dexamethasone after 9 months. The regimen...

RA Experts Highlight Key Developments Over the Past Year

A massive Swedish cohort study suggesting that biologic agents reduce the known excess risk of lymphoma in patients with rheumatoid arthritis was hailed as one...

Maternal Chronic Conditions Predict Cerebral Palsy in Offspring

Several maternal chronic conditions increase the risk of giving birth to a child with cerebral palsy, based on data from more than 1.3 million Norwegian...

CAR T-cell Products Shine, Reveal New Insights

Real-world experience with chimeric antigen receptor (CAR) T-cell therapies for large B-cell lymphomas compares favorably with experience in commercial and trial settings and provides new...