Tag: heart failure

‘Quadpill’ Bests Monotherapy for Initial BP Lowering: QUARTET

A “quadpill” containing quarter doses of four blood pressure (BP)-lowering medications was more effective than monotherapy for initial treatment of hypertension, with similar tolerability, in...

LOOP Trial Undercuts Long-term Continuous ECG Screening for AF

Maybe short, asymptomatic bouts of atrial fibrillation (AF) that show up on long-term, continuous monitoring aren’t worth hunting for just so oral anticoagulation (OAC) can...

Low-to-Moderate Coffee Intake in Midlife Tied to Heart Benefits

Among middle-aged people without heart disease, drinking up to 3 cups of coffee per day was associated with a lower risk for stroke or death...

‘Ablate and Pace’ Cuts Mortality in HF, Permanent AF

When a patient has permanent atrial fibrillation (AF) and advanced heart failure (HF), rate control therapy is an option but an “ablate-and-pace” strategy may be...

Finerenone Cuts CV Risk in T2D Across CKD Spectrum

New data on using the nonsteroidal mineralocorticoid receptor antagonist (MRA) finerenone to treat patients with type 2 diabetes and chronic kidney disease did more than...

ICMs Detect Serious Arrhythmias in High-Risk Post-MI: SMART-MI

After a myocardial infarction, implantable cardiac monitors (ICMs) are sensitive for detecting serious arrhythmias in patients with cardiac autonomic dysfunction but only moderately reduced left...

‘High Normal’ Sodium, Poor Hydration Linked to Heart Failure

Having a “high normal” serum sodium level in midlife, which reflects less than optimal fluid intake, is associated with an increased risk for left ventricular...

Patients With More Severe PH in COPD May Respond to Treatment

Patients with pulmonary hypertension (PH) as a complication of chronic obstructive pulmonary disease (COPD) have worse functional impairment and higher mortality, compared with patients who...

FDA Clears New Enzyme Replacement Therapy for Pompe Disease

The US Food and Drug Administration (FDA) has approved a new enzyme replacement therapy, avalglucosidase alfa (Nexviazyme, Genzyme), for patients aged 1 year and older...

Class I Recall of Boston Scientific INGENIO Family of Pacemakers

Boston Scientific has recalled the INGENIO family of pacemakers and cardiac resynchronization therapy pacemakers (CRT-Ps) because the devices may incorrectly transition to safety mode. Safety...

The FDA Knew the Heart Pumps Could Be Unsafe, Yet They Were Used

John Winkler II was dying of heart failure when doctors came to his hospital bedside, offering a chance to prolong his life. The HeartWare Ventricular...

Hospital Intervention Fails to Improve Heart Failure Outcomes

A clinical trial of an intervention designed to improve outcomes for patients hospitalized with heart failure shows that the strategy was not successful compared to...

Sleep Apnea Doubles Odds for Sudden Death

By Steven Reinberg HealthDay Reporter TUESDAY, Aug. 3, 2021 (HealthDay News) — With apologies to William Shakespeare, this is the stuff bad dreams are made...

HF Med Cornucopia Center Stage in Upcoming ESC Guideline: Preview

Today there are so many evidence-based drug therapies for heart failure (HF) with reduced ejection fraction (HFrEF) that physicians treating HF patients almost don’t know...

Med School Built in Ruins Has First Graduates

The day Cali Clark, DO, graduated from high school, the country’s deadliest tornado in more than 60 years ripped a 6-mile path through her hometown....

Spouses Can Share Cardiac Event Risk

A study from Japan suggests that a history of cardiovascular (CV) events in a spouse may elevate risk for future CV events in the other...

IV Iron Can Save Costs in HF With Iron Deficiency in Analysis

Intravenous iron therapy was predicted to be highly cost-effective or even cost-saving when used in high-risk, iron-deficient patients with heart failure (HF) in each of...

Positive Top-Line Results for Empagliflozin in HFpEF

Treatment with the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin (Jardiance, Boehringer Ingelheim/Eli Lilly) significantly reduces the risk of cardiovascular death or hospitalization for heart failure...

HF Med Undertreatment Due to Older Age Common, Flouts Evidence

Advanced age by itself can be a reason physicians hold back on prescribing mainstay medications, or not uptitrate them per guidelines, to their older patients...

Iron-Clad Benefits of CRT Seen in Reduced-EF Heart Failure

The case for the use of intravenous iron therapy for some patients with heart failure (HF) and reduced ejection fraction (HFrEF) has strengthened in recent...

Assays May Guide SGLT2 Inhibitor Use in High CV-Risk Diabetes

Heart failure (HF) guidelines and practice have been quick to embrace the sodium-glucose cotransporter 2 (SGLT2) inhibitor drug class after DAPA-HF, EMPEROR-Reduced, and other trials...

Bariatric Surgery’s Cardiovascular Benefit Extends to 7 Years

Patients with obesity who had bariatric surgery had a lower risk of having a major adverse cardiovascular event (MACE) or dying from all causes during...

More Evidence Links COVID Vaccines to Rare Myocarditis in Youth

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Swelling of the heart appears to be a very rare side...

Evidence Builds for iPhone 12 Interference With Cardiac Devices

Further evidence that powerful magnets in some Apple iPhones can interfere with cardiac implantable electronic devices (CIEDs) comes from a small study that also suggests...

Dispatch System Boosts Bystander CPR in Those With Limited English

The improved Los Angeles medical dispatch system prompted more callers with limited English proficiency to initiate telecommunicator-assisted cardiopulmonary resuscitation (T-CPR), compared with the previous system,...