Tag: glucocorticosteroids

Rituximab Superior to Mycophenolate Mofetil in Pemphigus Vulgaris Study

Mycophenolate mofetil, commonly used as a first-line corticosteroid-sparing agent for moderate to severe cases of the autoimmune blistering skin condition pemphigus vulgaris, has been found...

Lower Steroid Dose Proves Effective for New-Onset ANCA Vasculitis

A reduced dose of prednisolone plus rituximab was as effective as a conventionally high dose in treating patients with newly diagnosed antineutrophil cytoplasmic antibody (ANCA)–associated...

IM, IA Steroid Injections Prove Noninferior in Knee OA

Intramuscular injections of glucocorticoids have efficacy similar to that of intra-articular injections in reducing pain in knee osteoarthritis but without the concerns about joint infection...

Patients With Early Arthritis May Need Tailored Treatments

Patients with early, undifferentiated arthritis may benefit from milder or stronger treatments, depending on the number of their risk factors for developing rheumatoid arthritis, researchers...

Dexamethasone Harmful in Chronic Subdural Hematoma

A commonly used treatment for chronic subdural hematoma appears to be doing more harm than good, a new randomized trial has shown. The results show...

Proposed RA Guidelines: Maximize Methotrexate Before Switching

New proposed guidelines for managing rheumatoid arthritis (RA) recommend that methotrexate (MTX) be used aggressively before other treatment options. Dr Liana Fraenkel Previous guidelines, last...

Even Low-Dose Glucocorticoids Up Infection Risk in RA

Even low-dose glucocorticoids (GCs) are associated with a small but significant increased risk for infection among hospitalized patients with rheumatoid arthritis (RA), a study has...

AFF With Bisphosphonates Highest in Asians, Study Confirms

The latest findings regarding the risk for atypical femur fracture (AFF) with use of bisphosphonates for osteoporosis show a significant increase in risk when treatment...

Guidance Covers Glycemia in Dexamethasone-Treated COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. New guidance from the UK National Diabetes COVID-19 Response Group addresses...

Combination Therapy Quells COVID-19 Cytokine Storm

Treatment with high-dose methylprednisolone plus tocilizumab (Actemra, Genentech) as needed was associated with faster respiratory recovery, a lower likelihood of mechanical ventilation, and fewer in-hospital...

Patients on Steroids With COVID-19 Might Need Rescue Steroids

Endocrinologists have underlined the importance that physicians consider “a stress dose” of glucocorticoids in the event of severe COVID-19 infection in endocrine, and other, patients on...