Tag: genetics

Polygenic-Variant Testing Can Help Improves Glaucoma-Risk Prediction

NEW YORK (Reuters Health) – Polygenic risk scores can improve risk stratification in people at increased odds of developing open-angle glaucoma (OAG), according to researchers...

Caffeine May Raise Risk of Inherited Glaucoma

June 10, 2021 — People who drink a lot of caffeine have a higher risk of glaucoma, but only if their genes already make...

Gene Variant Confirmed as Strong Predictor of Lung Disease in RA

Patients with rheumatoid arthritis who carry a specific allele of the gene MUC5B have about double the risk of developing interstitial lung disease when compared...

Recommendations Presented for Rare Autoinflammatory Diseases

As researchers learn more about the genetic etiology of immunopathology, they have been able to more clearly understand rare but debilitating autoinflammatory conditions in ways...

First Drug for Lung Cancer With KRAS Mutation Gains FDA Approval

The first drug to target KRAS mutations in non-small cell lung cancer (NSCLC) has been approved by the US Food and Drug Administration. KRAS mutations...

Coffee Intake May Be Driven by Cardiovascular Symptoms

An examination of coffee consumption habits of almost 400,000 people suggests that those habits are largely driven by a person’s cardiovascular health. Data from a...

Maternal Chronic Conditions Predict Cerebral Palsy in Offspring

Several maternal chronic conditions increase the risk of giving birth to a child with cerebral palsy, based on data from more than 1.3 million Norwegian...

FDA OKs First ‘Targeted Treatment’ for Rare DMD Mutation

The US Food and Drug Administration (FDA) has approved the antisense oligonucleotide casimersen (Amondys 45, Sarepta Therapeutics) injection for the treatment of patients with Duchenne...

Variants Spur New FDA Guidance on COVID Vaccines, Tests, Drugs

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. The US Food and Drug Administration (FDA) on Monday updated its...

Daytime Napping May Be in Your Genes

MONDAY, Feb. 15, 2021 (HealthDay News) — If you like to take a snooze in the afternoon, your genes may explain your love of daytime...

Data ‘Favorable’ That Vaccines Limit Transmission

Researchers know by now the available COVID-19 vaccines prevent people from getting COVID around 95% of the time. But the million-dollar question remains: Are people...

COVID-19 Bill Would Scale Up Ability to Spot Virus Mutations

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. WASHINGTON (AP) — U.S. scientists would gain vastly expanded capabilities to...

Genetic Deletions Drive SARS-CoV-2 Antibody ‘Escape’

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Recurrent genetic deletions in the SARS-CoV-2 spike protein can change the...

Common Genetic Disorder Tied to Increased Dementia Risk in Men

Men with iron overload due to hereditary hemochromatosis are at increased risk of developing dementia, an analysis of UK Biobank data indicates. Results of a...

California Urges Stop to 300K COVID-19 Vaccines After Some Fall Ill

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. LOS ANGELES (AP) — California’s state epidemiologist is urging a halt...

Wisconsin Pharmacist Thought Vaccine Was Unsafe

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. MADISON, Wis. (AP) — A Wisconsin pharmacist convinced the world was...

Lp(a) and LPA Gene Score ‘Modest’ Predictors of CVD Risk

Although lipoprotein(a) (Lpa) levels and LPA genetic risk scores are both significantly associated with atherosclerotic cardiovascular disease (ASCVD) events, they appear to offer only a...

Virus ‘Endemic,’ Expect More Variants, Vaccine Tweaks

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. After a new, potentially more easily transmissible genetic variant of SARS-CoV-2...

COVID-19 Vaccines and Cancer Patients: 4 Things to Know

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Earlier this week, Medscape spoke with Nora Disis, MD, about vaccinating...

Two Twins, Different COVID-19 Trajectories

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Twin brothers in Italy developed symptoms of COVID-19 on the same...

Low Plasma Transthyretin Linked to Risk of Heart Failure

Low plasma transthyretin, also known as prealbumin, is associated with incident heart failure in the general population, new research suggests. In two prospective, population-based studies...

FDA Clears First Drug for Rare Genetic Causes of Severe Obesity

The US Food and Drug Administration (FDA) has approved setmelanotide (Imcivree, Rhythm Pharmaceuticals) for weight management in adults and children as young as 6 years...

Are We Close to Predicting Treatment-Free Remission in CML?

A recent study in the British Journal of Haematology by Irani and colleagues suggests that an effector-suppressor score, which is calculated using absolute natural killer (NK) cell,...

New Risks of Prescription Opioids Discovered

Prescription opioid use increases the risk for major depressive disorder (MDD) and anxiety and stress-related disorders (ASRD), new genetic evidence shows. The findings also suggest...

Triple Combination Benefits CF Patients With Advanced Disease

New CFTR [cystic fibrosis transmembrane conductance regulator] modulator therapies can offer life-altering benefits to some patients with cystic fibrosis, even those with advanced disease. Triple...