Tag: endocrine therapy

‘Treat Youth With Gender Dysphoria as Individuals’

Young people with gender dysphoria should be considered as individuals rather than fall into an age-defined bracket when assessing their understanding to consent to hormone...

Hormone Pellet Safety Data ‘Not Very Reassuring at All’ for Women

Women who receive pellet hormonal therapy may be significantly more likely to have side effects such as mood swings, anxiety, breast tenderness, hair pattern change,...

IL-6 Levels Predict Distant Breast Cancer Recurrence

The inflammatory cytokine interleukin 6 may be a biomarker for distant recurrence of breast cancer among patients treated for stage II-III HER2-negative disease, investigators have...

Pandemic Leads Doctors to Rethink Unnecessary Treatment

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Covid-19 is opening the door for researchers to address a problem...

Chemoimmunotherapy in Invasive Lobular Breast Cancer

The PD-L1 inhibitor atezolizumab (Tecentriq) combined with carboplatin has shown signs of clinical activity in women with metastatic invasive lobular breast cancer (ILC) according to...

Quicker Fertility Rebound in Young Women With Breast Cancer

For a young woman diagnosed with breast cancer, the prospect that the treatment needed for the cancer may irreversibly impair fertility piles on distress. A...

No Benefit Seen With Everolimus in Early Breast Cancer

Adding everolimus to adjuvant hormone therapy for early ER+, HER2- breast cancer does not offer any benefit over hormone therapy alone, according to results of...

CCR Score Can Guide Treatment After Radiation in Prostate Cancer

The combined clinical cell-cycle risk (CCR) score — derived from both clinical and genetic factors — can identify patients with intermediate- and high-risk localized prostate...

Increased Risk of Meningioma With Cyproterone Acetate Use

New details confirm an increased risk of developing intracranial meningiomas after prolonged use of the hormonal product cyproterone acetate. Cyproterone acetate is a synthetic progestogen...

First Mammography Guidelines for Older Breast Cancer Survivors

The first guidelines ever released for screening mammography for older survivors of breast cancer (>75 years) recommend that routine mammography be discontinued for women whose...

No Need to Stop Estrogen in Transgender Women Before Gender-Affirming Surgery

NEW YORK (Reuters Health) – Transgender women can safely maintain their estrogen hormone therapy during gender-affirming surgery without an increased risk of venous thromboembolism (VTE),...

Entinostat Doesn’t Overcome Endocrine Resistance in Breast Cancer

The histone deacetylase (HDAC) inhibitor entinostat failed to overcome resistance to endocrine therapy in hormone receptor–positive, HER2-negative, advanced breast cancer in a phase 3 trial....

Even More Women May Forgo Chemo for Breast Cancer

More women with early-stage breast cancer may safely forgo chemotherapy, suggests an interim analysis that had a median follow-up of 5 years of the large-scale...

Palbociclib Disappoints in HR+, HER2– Breast Cancer

The CDK4/6 inhibitor palbociclib provides no significant benefit in patients with hormone receptor–positive (HR+), HER2-negative primary breast cancer, according to first results from the PENELOPE-B...

What’s Hot, Including a Major Chemotherapy Trial

The “hottest” presentation at the upcoming 2020 San Antonio Breast Cancer Symposium (SABCS) comes from RxPONDER (abstract GS3-00), a major randomized clinical trial assessing use...

Transgender Cancer Patients May Not Realize Treatment Can Interact With Their Hormone Therapy

NEW YORK (Reuters Health) – Transgender cancer patients often were not told of potential interactions between cancer treatment and gender-affirming hormone therapy, a case series...

Hold Off Radiotherapy After Prostate Cancer Surgery

Most men who undergo radical prostatectomy can skip adjuvant radiotherapy and can be followed with observation alone. They can undergo early salvage radiotherapy if the...

Dermatologists’ Key Role in Transforming Transgender Patients

Whether they realize it or not, dermatologists play a key role in the physical transformation of transgender patients, according to Doris Day, MD. While clinical management...

Cognitive Decline With Endocrine Tx for Breast Ca

Cognitive impairment seen in women with early breast cancer who undergo chemotherapy ― so-called chemobrain ― has now been reported in patients who are treated...

‘Encouraging’ Results With Pre-Op Therapy for DCIS

First-of-its-kind findings suggest that hormonal therapy could be the primary treatment instead of surgery for women who are diagnosed with a precursor of breast cancer,...

COVID-19 Breast Cancer Patient Triage Guidelines (CPBCC)

What your doctor is reading on Medscape.com: APRIL 08, 2020 — The guideline on COVID-19–related triage of patients with breast cancer was released on...