Tag: drug/treatment safety

Cerebral Thrombosis After COVID Vax Deadlier Than Sporadic Form

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The cerebral venous thrombosis (CVT) that occurs as part of the...

Three JAK Inhibitors Get Boxed Warnings, Modified Indications

The arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR) poses an increased risk of serious cardiac events such as heart attack or stroke, cancer,...

FDA’s Fast-Track Approval Exposed as Lax, in Need of Reform

Since the US Food and Drug Administration (FDA) established its accelerated drug approval pathway 28 years ago, more than 2 in 5 drugs granted fast-track...

Three New Drugs Implicated in ANCA-Associated Vasculitis

The overactive bladder treatment mirabegron (Myrbetriq) is one of three new drugs to be linked to cases of drug-associated antineutrophil cytoplasmic antibody–associated vasculitis (DA-AAV) according...

Cancer Drugmaker Destroyed Records Before FDA Inspection

A company that manufacturer ingredients for cancer drugs used in the United States has pleaded guilty to concealing and destroying records prior to an inspection...

ICI for Cancer Ups Cardiac Event Risk: Danish Data

Immune checkpoint inhibitors (ICIs) increase the risk of cardiac events, including fatal heart attack and stroke, in patients with cancer, an analysis of Danish national...

Improvements in Chronic Hand Eczema Seen With Oral Gusacitinib

Gusacitinib, a novel oral inhibitor of multiple inflammatory pathways, achieved rapid and clinically meaningful improvement in corticosteroid-refractory moderate to severe chronic hand eczema in a...

FDA Issues New NSAIDs Warning for Second Half of Pregnancy

The US Food and Drug Administration released new warnings today that most nonsteroidal anti-inflammatory agents (NSAIDs) carry an elevated risk for kidney complications in an...

Chronic, Preventive Care Fell as Telemedicine Soared During COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. As the COVID-19 pandemic drove down the number of primary care...

Reworked OxyContin Fails to Cut Overall Abuse, FDA Panel Says

The long-awaited post-marketing studies of the abuse-deterrent formulation (ADF) of OxyContin (Perdue Pharma L.P.) received mixed reviews from a US Food and Drug Administration (FDA)...

FDA Requiring Opioid Labels to Urge Naloxone Co-prescribing

In a long-anticipated policy change, the US Food and Drug Administration (FDA) will now require manufacturers of opioids to urge clinicians toco-prescribe the overdose antidote...

No Benefit of Diabetes Drug Ertugliflozin in CV Outcomes Trial VERTIS

The sodium-glucose transporter 2 (SGLT-2) inhibitor ertugliflozin broke ranks with the other drugs in its class and failed to produce statistically significant drops in the...

Trending Clinical Topic: Remdesivir

What your doctor is reading on Medscape.com: APRIL 24, 2020 — As the COVID-19 pandemic continues, efforts to identify a safe and effective therapy...

Remdesivir Data Published, World Leader Recovers

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. Compassionate Use of Remdesivir More than two thirds of severely ill...

What Do Early Remdesivir Data Suggest?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. New data on the investigational antiviral drug remdesivir (Gilead) suggest clinical...

Chloroquine, Zinc Trials Underway for COVID-19 Prophylaxis

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. In the United States and Europe, a handful of clinical trials have begun...

Return-to-Work Guidelines, Tips From Frontline Docs

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. Here are the coronavirus stories Medscape’s editors around the globe think...

Parasite Drug Shows Early Promise Against COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. An inexpensive drug used to treat parasitic infections killed the coronavirus that causes...