Tag: drug development

Once-Nightly Sodium Oxybate Agent Effective in Narcolepsy

A novel, once-nightly formulation of sodium oxybate is safe and effective for treating both subjective and objective symptoms of narcolepsy, new research suggests. Top-line results...

Potential First-in-Class Schizophrenia Drug Cuts Negative Symptoms

The novel antipsychotic agent SEP-363856 (Sunovion Pharmaceuticals) has a significant and ongoing effect on negative symptoms in patients with schizophrenia, new research shows. Results of...

Novel S1P-Receptor Modulator Shows Promise in Phase 2b AD Trial

A novel, highly selective oral sphingosine 1-phosphate (S1P)–receptor modulator showed promise as a treatment for atopic dermatitis (AD) in a 12-week phase 2b trial, according...

Safety Profile for Novel CGRP Beats Standard of Care

Atogepant, an oral, small-molecule, calcitonin gene–related peptide receptor antagonist that’s been in development as a preventive treatment for chronic migraine, has been found to have...

First Pill for COVID-19 Could Be Ready by Year’s End

New pills to treat patients with COVID-19 are currently in midstage clinical trials and, if successful, could be ready by the end of the year....

Novel Alzheimer’s Drug Slows Cognitive Decline in Phase 2 Trial 

Results from a phase 2 placebo-controlled trial of the investigational antiamyloid drug donanemab show that the novel agent met the primary outcome of slowing cognitive...

Inhaled COVID Meds and ‘Simple, Self-Administered’ Care

  Aashish Manglik, MD, PhD, envisions a future in which inhaled medications provide a barrier to protect the nose and throat from invading pathogens, including...

Oral Antiviral Stops SARS-CoV-2 in its Tracks

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A single pill of the investigational drug molnupiravir taken twice a...

Biden Vows Enough COVID-19 Vaccine for Every Adult by End of May

March 2, 2021 — President Joe Biden on Tuesday said the United States will have enough COVID-19 vaccine doses to inoculate every American adult by May. In...

FDA Grants Emergency Use to Johnson & Johnson COVID-19 Vaccine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. And then there were three. The US Food and Drug Administration...

J&J COVID-19 Vaccine Wins Backing of FDA Panel

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. An FDA advisory panel lent their support today to a rapid...

FDA OKs First ‘Targeted Treatment’ for Rare DMD Mutation

The US Food and Drug Administration (FDA) has approved the antisense oligonucleotide casimersen (Amondys 45, Sarepta Therapeutics) injection for the treatment of patients with Duchenne...

COVID-19 Vaccines Were Rushed, but ‘All Steps Taken’

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Yes, the vaccines already authorized for emergency use against SARS-CoV-2 infection were developed relatively...

At Current Vaccination Pace, When Can US Expect Herd Immunity?

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It could take almost 9 more months to vaccinate 70% of Americans against SARS-CoV-2...

J&J Asks US Regulators to OK Its One-Shot COVID-19 Vaccine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Johnson & Johnson asked U.S. regulators Thursday to clear the world’s...

Studies Extend Hopes for Antibody Drugs Against COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. New results extend hopes for drugs that supply antibodies to fight...

FDA Grants Emergency Use for Moderna COVID-19 Vaccine

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. As expected, the US Food and Drug Administration granted Moderna an emergency use authorization...

FDA OKs Emergency Use of Pfizer COVID-19 Vaccine

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The US Food and Drug Administration (FDA) has authorized Pfizer/BioNTech’s COVID-19 vaccine for emergency...

Remdesivir Does Not Reduce COVID-19 Mortality, Study Says

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A large study sponsored by the World Health Organization found that...

Immunotherapy Drug Helping Lung Cancer Patients

By Robert Preidt HealthDay Reporter THURSDAY, Oct. 1, 2020 (HealthDay News) — A newly approved drug for the leading form of the number one...

Where Docs, Nurses Stand on COVID Emergency Use Authorizations

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Physicians and nurses in a Medscape poll indicated how likely they...

J&J’s One-Shot COVID-19 Vaccine Advances to Phase 3 Testing

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Johnson & Johnson (J&J) on Wednesday said it advanced into phase...

FDA OKs First-in-Class HIV Therapy for Patients With Few Options

The US Food and Drug Administration has approved fostemsavir (Rukobia, ViiV Healthcare), a first-in-class attachment inhibitor for the treatment of HIV-1 infection in adults. Fostemsavir...

‘Warp Speed’ Team Sticks by End-of-Year Vaccine Timeline

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Leaders of Operation Warp Speed (OWS), the White House’s team tasked...

First Vaccine Data, Antibody Test Issues

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Here are the coronavirus stories Medscape’s editors around the globe think...