Tag: corticosteroid

FDA Approves Anifrolumab (Saphnelo) as New Lupus Treatment

Anifrolumab, an inhibitor of type 1 interferons, received approval from the Food and Drug Administration for the treatment of adults with moderate to severe systemic...

SLE Neuropsych Event Etiology Helps Define Predictors, Outcomes

Different kinds of neuropsychiatric (NP) events in patients with systemic lupus erythematosus (SLE) have substantial variability in their occurrence, resolution, and recurrence over time, as...

Rituximab Superior to Mycophenolate Mofetil in Pemphigus Vulgaris Study

Mycophenolate mofetil, commonly used as a first-line corticosteroid-sparing agent for moderate to severe cases of the autoimmune blistering skin condition pemphigus vulgaris, has been found...

How Does Fragmented Care Affect IBD Outcomes?

Poor continuity of care may lead to worse outcomes among patients with active inflammatory bowel disease (IBD), according to data from more than 20,000 veterans....

RA Experts Highlight Key Developments Over the Past Year

A massive Swedish cohort study suggesting that biologic agents reduce the known excess risk of lymphoma in patients with rheumatoid arthritis was hailed as one...

Different MS Cognitive Phenotypes Could Help Guide Care

Researchers have developed a new classification of cognitive function for patients with multiple sclerosis (MS) that is based on the identification of five cognitive phenotypes....

Controversy Flares Over Ivermectin for COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The National Institutes of Health (NIH) has dropped its recommendation against...

Improvements in Chronic Hand Eczema Seen With Oral Gusacitinib

Gusacitinib, a novel oral inhibitor of multiple inflammatory pathways, achieved rapid and clinically meaningful improvement in corticosteroid-refractory moderate to severe chronic hand eczema in a...

Rilonacept Resolves, Prevents Pericarditis Recurrence

Results of a phase 3 trial show that treatment with rilonacept (Arcalyst), a drug already approved to treat inflammatory disease, both resolved acute episodes of...

Delgocitinib Successful for Hand Eczema in Phase 2b Trial

Delgocitinib cream shows a dose-dependent response in easing chronic hand eczema, a common and difficult-to-treat disorder for which few other topical options are available, new...

Don’t Discount Ultrapotent Topical Corticosteroids for Vulvar Lichen Sclerosus

Ultrapotent topical corticosteroids remain the core treatment for vulvar lichen sclerosus, although other therapies can be added, according to an expert speaking at the virtual...

Steroids Don’t Reduce Mortality in COVID-19 Patients With COPD

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Inhaled corticosteroids (ICS) do not protect patients with chronic respiratory conditions...

Dexamethasone for Macular Edema Unresponsive to Anti-VEGF

When diabetic macular edema does not improve with anti-vascular endothelial growth-factor (VEGF) therapy, a quick and complete switch to dexamethasone might help, results from a...

New Symptom, Test to Guide Steroid Treatment

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Here are the coronavirus stories Medscape’s editors around the globe think...

COVID-19 Update: Treatment Protocol, ICU Mortality

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Here are the coronavirus stories Medscape’s editors around the globe think...

Even a Few Days of Steroids May Be Risky, New Study Suggests

Extended use of corticosteroids for chronic inflammatory conditions puts patients at risk for serious adverse events (AEs), including cardiovascular disease, osteoporosis, cataracts, and diabetes. Now,...

Too Many Children Receive Opioids for Pneumonia and Sinusitis

A significant percentage of children receive opioids and systemic corticosteroids for pneumonia and sinusitis despite guidelines, according to an analysis of 2016 Medicaid data from...

Worse COVID-19 Outcomes in IBD Patients Taking Corticosteroids

NEW YORK (Reuters Health) – Corticosteroids appear to worsen COVID-19 outcomes in patients with inflammatory bowel disease (IBD), but TNF antagonists do not, according to...