Tag: coronary heart disease

Sickle-Cell Trait May Not Independently Elevate CHD Risk

African Americans with sickle-cell trait (SCT), that is, who are heterozygous for the sickle-cell gene variant, don’t as a result necessarily have an elevated risk...

‘Lipid Paradox’ Seen in Nonobese RA Patients With Low LDL

Dr George Karpouzas Oxidative stress may account for the “lipid paradox,” a higher incidence of heart disease burden found in nonobese rheumatoid arthritis (RA) patients...

Lp(a) and LPA Gene Score ‘Modest’ Predictors of CVD Risk

Although lipoprotein(a) (Lpa) levels and LPA genetic risk scores are both significantly associated with atherosclerotic cardiovascular disease (ASCVD) events, they appear to offer only a...

Ultraprocessed Food Again Linked to Increased CVD, Death

Yet another study has linked the consumption of ultraprocessed, or “junk,” foods to bad health outcomes. In a longitudinal analysis of more than 22,000 men...

LDL Not the Primary Culprit in ASCVD?

Two new studies suggest that low-density lipoprotein cholesterol (LDL-C) may be not the main driver of atherosclerotic cardiovascular disease (ASCVD). The findings instead implicate remnant...

Calcium Burden Drives CV Risk Whether CAD Is Obstructive or Not

Coronary artery calcium (CAC) score as a measure of plaque burden more reliably predicts future cardiovascular (CV) risk in patients with suspected coronary disease (CAD)...

Sedentary Postmenopausal Women Have Higher HF Risk

The more time older women spent sitting or lying down, the more likely their risk of hospitalization for heart failure, based on data from more...

Early Life Trauma Tied to Increased CVD Risk With MI History by Middle Age

(Reuters Health) – Young and middle-age adults with a history of myocardial infarction may have a higher risk of adverse cardiovascular outcomes when they also...

Remote, Non-Physician-Led Care Cuts LDL, BP in High-Risk Patients

A novel algorithm-based disease management program, led by pharmacists and nonlicensed navigators, optimized cholesterol and blood pressure levels in high-risk patients, according to an interim...

Statins Beneficial in Elderly, Guidelines Should Be Strengthened

Contrary to historical evidence, among older people, elevated LDL cholesterol levels increase risk for heart attack and cardiovascular disease, and older patients benefit as much,...

No Secondary Prevention Benefit With Omega-3s in Elderly

Omega-3 fatty acids on top of standard care did not reduce major cardiovascular events or death in elderly survivors of an acute myocardial infarction (MI)...

STRENGTH Trial Questions CV Benefit of High-Dose Omega-3s

Questions about the cardiovascular benefit of omega-3 fatty acids and the high-dose eicosapentaenoic acid (EPA) product, icosapent ethyl (Vascepa, Amarin), have resurfaced with the presentation...

Combined OCT, Cardiac MRI Unravels Root Cause in Most MINOCA

Optical CT (OCT) plus cardiac MRI (CMR) provides a more specific diagnosis in the majority of women presenting with myocardial infarction with nonobstructive coronary arteries...

Don’t Miss Cardiovascular Risk Factors in Transgender Patients

Cardiovascular disease risk is elevated among transgender individuals seeking gender-affirming hormone therapy, according to a retrospective study in 427 patients. The transgender population often experiences...

Simple Questionnaire Can Identify Silent Atherosclerosis

Individuals in the general population with high levels of silent coronary atherosclerosis can be successfully identified with a simple questionnaire that they can complete themselves...

Omega-3, Vit-D Both Fail at AF Primary Prevention in VITAL-Rhythm

Clinical trials of omega-3 fatty acid or vitamin D supplements have followed a long and winding road in search of benefits in cardiovascular (CV) disease,...

Lupus-Specific Predictors for CVD Described in Black Patients

Black patients with systemic lupus erythematosus (SLE) are known to have significantly elevated risk for stroke and ischemic heart disease (IHD), compared with non-Black patients...

Metabolic Surgery Post-MI Trims CV Events Long Term

Beyond the well-established benefits of sustained weight loss and improved type 2 diabetes, metabolic surgery performed after myocardial infarction (MI) lowered the long-term risk of...

Proinflammatory Dietary Pattern Linked to Higher CV Risk

Dietary patterns with higher inflammatory potential were significantly associated with a higher incidence of cardiovascular disease (CVD) and stroke in a new pooled analysis of...

3 Factors Predict Cardiac Events in Overdose Patients

A predictive rule that can help triage drug overdose patients for the risk for cardiac arrest, shock, ventricular dysrhythmias, or myocardial injury has been validated...

The ‘Grubby’ Affair of the EXCEL Trial and the European Guidelines

“I disapprove of what you say, but I will defend to the death your right to say it.” The choice of the secretary general of...

Women With Heterozygous FH Less Likely to Receive Treatment

There are gender differences among patients with heterozygous familial hypercholesterolemia (HeFH) in terms of when the disease is diagnosed, how it is treated, and the...

Study Questions Routine Long-term Beta-Blocker Post MI

Current American and European guidelines recommending long-term beta-blocker therapy following an acute MI appear to be obsolete in the modern reperfusion era, suggests an analysis...

Aspirin for Primary Prevention of CVD in Rheumatic Diseases

Low-dose aspirin may be considered for the primary prevention of cardiovascular disease (CVD) in patients with autoimmune systemic rheumatic diseases who are at particularly high...

Novel Type 2 Diabetes Drugs Incur High Costs in Medicare

Switching Medicare beneficiaries who have type 2 diabetes to one of the novel glucose-lowering medications could dramatically raise their out-of-pocket costs, thereby potentially hindering adherence,...