Tag: clinical trials

No Evidence That SNRIs Relieve Back Pain

While some guidelines support serotonin norepinephrine reuptake inhibitors (SNRIs) as treatments for back pain, a new systematic review and meta-analysis of existing research found no...

Controversy Flares Over Ivermectin for COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The National Institutes of Health (NIH) has dropped its recommendation against...

ACEIs, ARBs Safe to Continue in COVID-19: Trial Published

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The BRACE-CORONA trial ― the first randomized trial to address the...

Nasal Spray Vaccine for COVID-19 in Early Trials

TUESDAY, Jan. 19, 2021 (HealthDay News) — A spritz instead of a shot to ward off COVID-19? Researchers report that a nasal spray vaccine against...

FDA Welcomes Sotagliflozin Data for Heart Failure in Diabetes

The Food and Drug Administration has determined that data collected on the dual SGLT1/2 inhibitor sotagliflozin (Zynquista) for treating patients with type 2 diabetes in...

J&J COVID-19 Vaccine on Track for March Rollout, Still Aims for 1 Bln Doses This Year: Exec

CHICAGO (Reuters) – Johnson & Johnson is on track to roll out its single-shot coronavirus vaccine in March, and plans to have clear data on...

Labor Induction at 41 Weeks Tied to Lower Morbidity, Mortality Than Expectant Management

(Reuters Health) – Inducing labor at 41 weeks may result in a lower risk of severe adverse perinatal and neonatal outcomes than expectant management until...

Mortality Higher in Real-World LVAD Recipients Ineligible for Clinical Trials

NEW YORK (Reuters Health) – Roughly half of patients with advanced heart failure who receive a left ventricular assist device (LVAD) in clinical practice do...

Agency Kept Independence With Science as Its ‘North Star’

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Some Trump administration appointees have resigned in protest of the riot...

After 48 Years, NCI Aims to Track Breast Cancer Recurrences

  Patients with breast cancer want accurate information on the risk of their cancer recurring once they have completed treatment. “I would like to know...

Dexamethasone Harmful in Chronic Subdural Hematoma

A commonly used treatment for chronic subdural hematoma appears to be doing more harm than good, a new randomized trial has shown. The results show...

Experts Debate Wisdom of Delaying Second COVID-19 Vaccine Dose

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A proposal to delay administration of the second dose of COVID-19 vaccines — suggested...

Bringing Traditional Healing Under the Microscope in South Africa

Traditional healer and national coordinator of the Traditional Healers Organisation (THO) of South Africa, Phephisile Maseko, treats patients with a mix of cannabis and other...

Doctors Underreport Side Effects of Breast Irradiation

There is a substantial mismatch between patient and physician reports of toxicity during radiotherapy for breast cancer, according to an analysis of nearly 10,000 U.S....

United States Buys 100 Million More Pfizer Vaccine Doses

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Trump administration is buying 100 million additional doses of the...

Pregnancy Does Not Increase Seizures in Women With Epilepsy

Women with epilepsy do not have an increased seizure rate during pregnancy as long as they have their medication levels carefully monitored, a new study...

Sex Differences Found in Post-CABG Mortality

A new study shows sex differences in mortality rates among patients undergoing coronary artery bypass grafting (CABG). The researchers found that 7 years after a...

Type 1 Diabetes Screen Costing $55 Is Launched in US

A new initiative launched by the diabetes charity JDRF aims to broaden screening for type 1 diabetes risk for the general population of the United...

Temper Enthusiasm for Long-term Treatment With Bisphosphonates?

Women treated with oral bisphosphonate drugs for osteoporosis for 5 years get no additional benefit ― in terms of hip fracture risk ― if the...

Shared Medical Appointments May Bridge the Opioid Treatment Gap

Shared medical appointments (SMAs) are an acceptable way to receive treatment for opioid use disorder (OUD), new research suggests. In a survey study, participants attending...

Coronavirus Has Infected Over 2% of US Children

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. After last week’s ever-so-slightly positive news, the COVID-19 numbers in children...

Even More Women May Forgo Chemo for Breast Cancer

More women with early-stage breast cancer may safely forgo chemotherapy, suggests an interim analysis that had a median follow-up of 5 years of the large-scale...

Baricitinib Combo for COVID-19 Accelerates Recovery, Study Shows

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Among people hospitalized with COVID-19, a combination of baricitinib and remdesivir...

Russian State Employees Describe Pressure to Join Vaccine Trials

MOSCOW (Reuters) – In late September, Moscow municipal official Sergei Martyanov sent a series of text messages to his subordinates: “Colleagues!!!… What is this sabotage???”...

What’s Hot, Including a Major Chemotherapy Trial

The “hottest” presentation at the upcoming 2020 San Antonio Breast Cancer Symposium (SABCS) comes from RxPONDER (abstract GS3-00), a major randomized clinical trial assessing use...