Tag: clinical studies

Study IDs Most Common Lingering Symptoms 8 Months After Mild COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Loss of smell, loss of taste, dyspnea, and fatigue are the...

FDA Approves First AI Device to Detect Colon Lesions

The US Food and Drug Administration (FDA) on Friday announced its first-ever approval of an artificial intelligence device to help find colon lesions during colonoscopy....

Pfizer COVID-19 Vaccine Protects for 6 Months or More: Study

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Pfizer/BioNTech COVID-19 vaccine affords at least 6 months of protection...

Benefits of Drug for Women With Hyposexual Disorder Questioned

Bremelanotide, a Food and Drug Administration–approved treatment for acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women, may be of limited use, suggests Glen...

Novel Alzheimer’s Drug Slows Cognitive Decline in Phase 2 Trial 

Results from a phase 2 placebo-controlled trial of the investigational antiamyloid drug donanemab show that the novel agent met the primary outcome of slowing cognitive...

More Reassurance for Certain Antiseizure Drugs in Pregnancy

Further evidence supporting the safety of two antiseizure medications in pregnancy has come from a new study. The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic...

Delay Surgery by 7 Weeks After COVID Diagnosis, Study Shows

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Seven weeks appears to be the ideal amount of time to...

‘Stunning’ Report Shows Eating Disorders Are Vastly Underestimated

A “stunning” new analysis of global data on eating disorders show that they are far more prevalent and disabling than previously reported. Investigators found the...

Risdiplam Promising for Spinal Muscular Atrophy

Infants with type 1 spinal muscular atrophy (SMA) showed promising signs, including an increased expression of functional survival motor neuron (SMN) protein in the blood,...

Peanut Sublingual Immunotherapy Feasible and Effective in Toddlers

Sublingual immunotherapy for the treatment of peanut allergy is safe and effective, even in children as young as age 1 year. In a double-blind, placebo-controlled,...

NYC Officials Downplay Concern Over New Coronavirus Variant

NEW YORK (Reuters) – Mayor Bill de Blasio’s chief medical adviser on Thursday downplayed the results of two studies that may suggest a new coronavirus...

NfL Levels Linked to Worse Disability in Real-World MS

Elevations in serum neurofilament light chain levels (sNfL) in people with multiple sclerosis (MS) are significantly linked to worse neurologic function, clinical disability, and lower...

FDA Places Clinical Hold on Sickle Cell Gene Therapy

The FDA placed a clinical hold yesterday on two gene therapy trials for sickle cell disease (SCD) after one participant developed acute myeloid leukemia (AML)...

Late-Window Stroke Thrombolysis Not Linked to Clot Migration

In patients with acute ischemic stroke, the use of thrombolysis in the late window of 4.5 to 9 hours after symptom onset was not associated...

Expect Steady Rise in US Supply

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The United States might possibly have a surplus of COVID-19 vaccines...

Bladder Cancer Indication Withdrawn for Durvalumab

After failing to improve overall survival in unresectable metastatic bladder cancer in a phase 3 trial, this indication will be withdrawn in the United States...

Outcomes Have Improved for PAH in Connective Tissue Disease

Survival rates for patients with pulmonary arterial hypertension associated with connective tissue diseases have improved significantly in recent years, and there is growing evidence that...

Long-COVID in Children: It’s a Thing

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. COVID-19 may be causing long-term symptoms in children, according to a...

COVID-19 Vaccines Were Rushed, but ‘All Steps Taken’

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Yes, the vaccines already authorized for emergency use against SARS-CoV-2 infection were developed relatively...

SARS-CoV-2 Antibody Tests Most Sensitive in Men, Middle Aged

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Tests to detect antibodies to SARS-CoV-2 are most sensitive among people...

CCR Score Can Guide Treatment After Radiation in Prostate Cancer

The combined clinical cell-cycle risk (CCR) score — derived from both clinical and genetic factors — can identify patients with intermediate- and high-risk localized prostate...

PFO Closure Reduces Migraine: New Meta-Analysis

A meta-analysis of two randomized studies evaluating patent foramen ovale (PFO) closure as a treatment strategy for migraine has shown significant benefits in several key...

Tofacitinib Linked to Risk for Cardiac Events, Cancer, FDA Warns

The Food and Drug Administration has alerted the public to an increased risk of serious heart-related problems and cancer risk associated with the Janus kinase...

Did Unrecognized Cardiac Amyloidosis Hinder Recent HFpEF Trials?

Screening for cardiac amyloidosis and excluding patients with cardiac amyloidosis from trials of new therapies for heart failure with preserved ejection fraction (HFpEF) may increase...

Which Patients With Kidney Cancer Are Likely to Respond to ICI?

Several factors associated with a diminished response to immune checkpoint inhibitor (ICI) drugs among patients with metastatic clear cell renal cell carcinoma (ccRCC) have been...