Tag: clinical studies

Sexual Assault in Women Tied to Increased Stroke, Dementia Risk

Traumatic experiences, especially sexual assault, may put women at greater risk for poor brain health. In the Ms Brain study, middle-aged women with trauma exposure...

Metformin Disappoints in Two Phase 2 Lung Cancer Trials

Although well tolerated, metformin does not improve survival when given alongside chemoradiotherapy to patients with locally advanced non–small cell lung cancer (NSCLC), and may even...

No Serious Health Risks in Large Study

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Serious health risks were no more common in the first 3...

AMA Calls for End to Ivermectin Use for COVID Amid Spike in Use

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. In a joint statement, the American Medical Association (AMA), American Pharmacists...

HIV Vaccine Fails, Prompting Calls for More PrEP

Last year, Katherine Gill, MD, an HIV prevention researcher in Cape Town, South Africa, realized how jaded she’d become to vaccine research when the Pfizer...

Building a Case for Personalized, Genome-Based Radiation Dosing

A team of researchers from the Cleveland Clinic, the Moffitt Cancer Center in Tampa, and Case Western Reserve University in Cleveland is zeroing in on...

Two Swings, Two Misses With Colchicine, Vascepa in COVID-19

The anti-inflammatory agents colchicine and icosapent ethyl (Vascepa; Amarin) failed to provide substantial benefits in separate randomized COVID-19 trials. Both were reported at the European...

Bystander Rescue Breathing CPR in Kids Tied to Better Survival

Children who receive CPR with both rescue breathing and compressions from a bystander have greater odds of survival without serious brain damage than if they...

Malaria Vaccine + Antimalarial = 70% Reduction in Disease, Death

A new study from Africa shows a remarkable 70% reduction in malaria if two treatments — a vaccine and an antimalarial medication — are combined...

‘Ablate and Pace’ Cuts Mortality in HF, Permanent AF

When a patient has permanent atrial fibrillation (AF) and advanced heart failure (HF), rate control therapy is an option but an “ablate-and-pace” strategy may be...

Long COVID Symptoms Can Persist for More Than 1 Year, Study Shows

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Nearly one half of people who are hospitalized with COVID-19 suffer...

Two Better Than One for Hip Replacement

A combination of two nerve blocks reduced immediate postsurgery opioid use in total hip arthroplasty (THA) patients by about 35% compared with use of a...

Flavonoid-Rich Foods, Aided by Gut Bacteria, Tied to Lower BP

A higher intake of flavonoid-rich foods such as berries, apples, tea, and red wine is associated with a clinically relevant reduction in blood pressure levels,...

Convalescent Plasma Didn’t Help High-Risk COVID Patients: NIH

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A study says convalescent plasma did not stop the progression of...

FDA Warns Again About Robotic Mastectomy, Breaks New Ground

The US Food and Drug Administration (FDA) today issued a new safety communication about the use of robotically assisted mastectomy, warning patients and physicians that...

‘Dawn of a New Era’ in the Treatment of Renal Cell Carcinoma

The decades-long search for a safe, effective adjuvant therapy for patients with resected kidney cancer at high risk of recurrence appears to have taken a...

Chronic Kidney Disease Tied to Worse LAAO Outcomes

The presence of chronic kidney disease (CKD) or end-stage renal disease (ESRD) is associated with worse in-hospital and short-term outcomes after left atrial appendage (LAA)...

Anti-Sperm Antibodies Tested as Contraceptive in Sheep

Antibodies that bind to sperm might be an effective nonhormonal method of contraception, at least according to early studies in sheep, researchers report. When researchers...

Just Trust Us on the COVID Booster

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Pfizer CEO Albert Bourla was confident in June about the ability...

Antibody Prevents Malaria in New Trial

A new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to 9 months in people who were...

Task Force Affirms Routine Gestational Diabetes Testing

Asymptomatic pregnant women with no previous diagnosis of type 1 or 2 diabetes should be screened for gestational diabetes at 24 weeks’ gestation or later,...

Journal Takes 3 Years to Act

  More than three and a half years after being alerted to concerns about the data in a 2015 article, an obstetrics journal has finally...

A Centuries Old ‘Superfood’ as Diabetes Treatment

If asked to think of a camel, many will invariably call up the emblematic image of a humped animal crossing the horizon in a blazing...

No Win for Milrinone Over Dobutamine in Cardiogenic Shock

A head-to-head randomized comparison of milrinone and dobutamine — the most used inotropes in cardiogenic shock therapy in North America — failed to find a...

Malaria Transmission in Africa Worsened by Small Dams

A recent study published in Nature’s Scientific Reports suggests that the size of dams in Africa is an important and overlooked factor in malaria transmission....