Tag: cardiovascular

Sickle-Cell Trait May Not Independently Elevate CHD Risk

African Americans with sickle-cell trait (SCT), that is, who are heterozygous for the sickle-cell gene variant, don’t as a result necessarily have an elevated risk...

New Data Strengthen Case for Prechemotherapy Statins

Evidence supporting the use of statins to protect against cardiotoxic chemotherapy has been strengthened with new data from a propensity-matched analysis. Among women with breast...

Study Finds AD Significantly Associated With Autoimmune Diseases

A diagnosis of atopic dermatitis in individuals ages 15 years or older, compared with controls without atopic dermatitis, was nearly twice as likely to be...

NETs a Possible Therapeutic Target for COVID-19 Thrombosis?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Researchers in Madrid may have found a clue to the pathogenesis...

Lp(a) and LPA Gene Score ‘Modest’ Predictors of CVD Risk

Although lipoprotein(a) (Lpa) levels and LPA genetic risk scores are both significantly associated with atherosclerotic cardiovascular disease (ASCVD) events, they appear to offer only a...

Risk Score to Guide ACS Treatment Does Not Improve Outcomes

In a cluster randomized clinical trial, routine use of the Global Registries of Acute Coronary Events (GRACE) risk score (GRS) to guide treatment decisions for...

Ultraprocessed Food Again Linked to Increased CVD, Death

Yet another study has linked the consumption of ultraprocessed, or “junk,” foods to bad health outcomes. In a longitudinal analysis of more than 22,000 men...

Novartis Receives FDA Complete Response Letter on Inclisiran

The US Food and Drug Administration (FDA) issued a complete response letter regarding Novartis’ new drug application (NDA) for inclisiran, a novel treatment for elevated...

LDL Not the Primary Culprit in ASCVD?

Two new studies suggest that low-density lipoprotein cholesterol (LDL-C) may be not the main driver of atherosclerotic cardiovascular disease (ASCVD). The findings instead implicate remnant...

Low Plasma Transthyretin Linked to Risk of Heart Failure

Low plasma transthyretin, also known as prealbumin, is associated with incident heart failure in the general population, new research suggests. In two prospective, population-based studies...

Peripheral Neuropathy Tied to Mortality in Adults Without Diabetes

Peripheral neuropathy is common in US adults and is associated with an increased risk of death, even in the absence of diabetes, researchers report today...

PFO Closure Beneficial in Stroke Patients With Thrombophilia

Thrombophilic patients who have had an ischemic stroke and have a patent foramen ovale (PFO) benefit from having the PFO closed, a new study suggests....

Calcium Burden Drives CV Risk Whether CAD Is Obstructive or Not

Coronary artery calcium (CAC) score as a measure of plaque burden more reliably predicts future cardiovascular (CV) risk in patients with suspected coronary disease (CAD)...

Incidence of Stroke, But Not MI, Increasing in Young People

Although the incidence of stroke is increasing steadily among young adults, the incidence of acute myocardial infarction (AMI) remains stable, a new analysis suggests. This...

USPSTF Continues to Back Behavioral Intervention to Cut CVD Risk

Adults with risk factors for cardiovascular disease (CVD) should be offered or referred for behavioral counseling to promote a healthy diet and physical activity, the...

Chili Pepper Consumption Linked to Better Midlife Survival

In a meta-analysis of four geographically diverse observational studies, a higher intake of any type of chili pepper was associated with a lower rate of...

Remote, Non-Physician-Led Care Cuts LDL, BP in High-Risk Patients

A novel algorithm-based disease management program, led by pharmacists and nonlicensed navigators, optimized cholesterol and blood pressure levels in high-risk patients, according to an interim...

Statins Beneficial in Elderly, Guidelines Should Be Strengthened

Contrary to historical evidence, among older people, elevated LDL cholesterol levels increase risk for heart attack and cardiovascular disease, and older patients benefit as much,...

No Extra Cardiopulmonary Event Reduction With High-Dose Flu Vac

The high-dose influenza vaccine was not more effective than a standard-dose vaccine in lowering the risk for death or hospitalizations for cardiac or pulmonary events...

STRENGTH Trial Questions CV Benefit of High-Dose Omega-3s

Questions about the cardiovascular benefit of omega-3 fatty acids and the high-dose eicosapentaenoic acid (EPA) product, icosapent ethyl (Vascepa, Amarin), have resurfaced with the presentation...

Polypill Provides Meaningful Primary CV Prevention

A once-daily polypill containing four drugs to lower blood pressure and LDL cholesterol reduced major adverse cardiovascular events by 21% relative to placebo in people...

Combined OCT, Cardiac MRI Unravels Root Cause in Most MINOCA

Optical CT (OCT) plus cardiac MRI (CMR) provides a more specific diagnosis in the majority of women presenting with myocardial infarction with nonobstructive coronary arteries...

Don’t Miss Cardiovascular Risk Factors in Transgender Patients

Cardiovascular disease risk is elevated among transgender individuals seeking gender-affirming hormone therapy, according to a retrospective study in 427 patients. The transgender population often experiences...

Simple Questionnaire Can Identify Silent Atherosclerosis

Individuals in the general population with high levels of silent coronary atherosclerosis can be successfully identified with a simple questionnaire that they can complete themselves...

Omega-3, Vit-D Both Fail at AF Primary Prevention in VITAL-Rhythm

Clinical trials of omega-3 fatty acid or vitamin D supplements have followed a long and winding road in search of benefits in cardiovascular (CV) disease,...