Tag: cancer

No Benefit Seen With Everolimus in Early Breast Cancer

Adding everolimus to adjuvant hormone therapy for early ER+, HER2- breast cancer does not offer any benefit over hormone therapy alone, according to results of...

How Patients Decide on Surgery

Patients consider the risk of cancer and menopause, as well as other factors, when making decisions about ovarian cancer prevention surgery, according to a small...

Cancer Drugmaker Destroyed Records Before FDA Inspection

A company that manufacturer ingredients for cancer drugs used in the United States has pleaded guilty to concealing and destroying records prior to an inspection...

At-Home HPV Swab Tests for Cervical Screening in UK Trial

A trial of an at-home human papillomavirus (HPV) swab test has begun in London, United Kingdom, as part of an initiative to increase uptake of...

No Survival Benefit to Primary Resection Before Chemo in CRC

NEW YORK (Reuters Health) – Contrary to previous reports, primary tumor resection prior to chemotherapy did not confer a survival benefit in colorectal cancer patients...

Why Is Liver Cancer More Lethal for Black Patients?

By Denise Mann HealthDay Reporter THURSDAY, Feb 26, 2021 (HealthDay News) — Black people with hepatitis C develop liver cancer sooner than people in...

US Cancer Drug Approvals Ensure Access but Not Value

Cancer drugs that have been approved in the United States are often not immediately approved in the United Kingdom and Canada, owing to uncertainty over...

FDA Places Clinical Hold on Sickle Cell Gene Therapy

The FDA placed a clinical hold yesterday on two gene therapy trials for sickle cell disease (SCD) after one participant developed acute myeloid leukemia (AML)...

Cancer Patients Worry Pandemic Will Impact Care

By Robert Preidt HealthDay Reporter WEDNESDAY, Feb. 24, 2021 (HealthDay News) — Battling cancer is tough in normal times, but many U.S. cancer survivors are...

Bladder Cancer Indication Withdrawn for Durvalumab

After failing to improve overall survival in unresectable metastatic bladder cancer in a phase 3 trial, this indication will be withdrawn in the United States...

Heartburn Raises Odds for Esophageal, Larynx Cancers

It’s possible, Abnet said, that similar mechanisms could also contribute to squamous cell carcinoma in the esophagus and to laryngeal cancer. Whether treating GERD...

CCR Score Can Guide Treatment After Radiation in Prostate Cancer

The combined clinical cell-cycle risk (CCR) score — derived from both clinical and genetic factors — can identify patients with intermediate- and high-risk localized prostate...

Liquid vs Tissue Biopsy in Prostate Cancer: Why Not Both?

The genomic landscape of circulating tumor DNA (ctDNA) was comparable to the landscape of tissue biopsies in a large study of patients with metastatic castration-resistant...

Does Cancer Care Inspire Great Writing?

Oncologists face unique emotional challenges because of the frequency of the morbidity and mortality they see, which may be unparalleled among specialists. “We see tragedy...

Amivantamab Shows Promise in Challenging EGFR-Mutated NSCLC

A novel drug, the immune cell-directing antibody amivantamab (under development by Janssen), has shown promise for the treatment of patients with non–small cell lung cancer...

Genetic Deletions Drive SARS-CoV-2 Antibody ‘Escape’

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Recurrent genetic deletions in the SARS-CoV-2 spike protein can change the...

CART T Elicits Strong Response for Multiple Myeloma

Dec. 9, 2020 — For patients with heavily-pretreated multiple myeloma, the strong responses seen with the new (CAR T-cell treatment ciltacabtagene autoleucel (cilta-cel) have also...

Tofacitinib Linked to Risk for Cardiac Events, Cancer, FDA Warns

The Food and Drug Administration has alerted the public to an increased risk of serious heart-related problems and cancer risk associated with the Janus kinase...

MRI-Guided Prostate Biopsy Prevails in PRECISE Trial

Here’s welcome news for men of a certain age: new results support a less invasive approach to investigations for suspicion of prostate cancer. An approach...

Which Patients With Kidney Cancer Are Likely to Respond to ICI?

Several factors associated with a diminished response to immune checkpoint inhibitor (ICI) drugs among patients with metastatic clear cell renal cell carcinoma (ccRCC) have been...

Fecal Transplant Overcomes Resistance to Immunotherapy

For some patients with advanced melanoma whose conditions had stopped responding to immunotherapy, response was restored after treatment with fecal transplants. The material for the...

Breast Cancer Now the Leading Cancer Diagnosis

THURSDAY, Feb. 4, 2021 (HealthDay News) — Breast cancer has surpassed lung cancer as the world’s most commonly diagnosed cancer. In 2020, there were...

Metformin Could Help Prevent Some Breast Cancers

More study is needed to better understand whether there is a cause-effect relationship between metformin and cancer or whether the increased risk owes to an...

Tofacitinib for RA Misses the Mark in Safety Study

Daily treatment with tofacitinib (Xeljanz) led to more malignancies and adverse cardiovascular events in older rheumatoid arthritis patients compared with treatment with a tumor necrosis...

Liquid Biopsies Helpful in Prostate Cancer, but Most Not Ready for Routine Use

NEW YORK (Reuters Health) – Liquid biopsies have the potential to guide therapeutic decision making in prostate cancer, but issues such as assay standardization, cost...