Tag: biomarker

‘Calcium Imbalance’ Linked to Bipolar Severity

Calcium homeostasis may play a role in bipolar disorder (BD) severity, with raised serum vitamin D and parathyroid hormone (PTH) levels linked to worse clinical...

Blood Biomarker a ‘Promising Predictor’ of Psychosis Relapse

Copeptin, a small peptide secreted with the hormone vasopressin, appears to be one of the first promising biomarkers for predicting psychosis relapse, results of an...

Motor Abnormalities a Harbinger of Serious Mental Illness?

Motor problems in children may be a harbinger of serious mental illness, new research suggests. Investigators found that motor abnormalities were twice as common among...

A New Biomarker of Traumatic Brain Injury?

Plasma levels of von Willebrand factor may be a useful biomarker of traumatic brain injury (TBI) and its severity, new research suggests. “Reliable detection of...

Heart Rate Variability a Biomarker of Bipolar Disorder Severity?

Reduced heart rate variability (HRV) is associated with severity in patients with bipolar disorder (BD), in terms of both individual and overall measures of disease...

Evobrutinib May Help Reduce MS Nerve Damage

Oral evobrutinib, an investigational highly selective Bruton’s tyrosine kinase inhibitor, may have a beneficial effect on reducing nerve damage in multiple sclerosis (MS), based on how...

New Test Could Help Primary Care Docs Chart Kidney Disease

A novel test that estimates the risk of a patient with type 2 diabetes developing end-stage kidney disease significantly outperformed more conventional risk-prediction methods in...

Can a ‘Sweat Sticker’ Improve Diagnosis of Cystic Fibrosis?

A soft, flexible device that sticks on skin to capture sweat and measure sweat chloride may help doctors diagnose cystic fibrosis in infants, according to...

Testosterone Decline After Steroid Abuse Revealed With Biomarker

Levels of insulinlike factor 3 (INSL3) drop noticeably in men who have abused anabolic androgenic steroids (AAS), even well after stoppage. The results suggest that...

Blood Test Predicts Organ Rejection Risk After Kidney Transplant

A functional immunologic assay that could easily be incorporated into routine laboratory work can predict which patients are at high risk for rejection of their...

NYC Officials Downplay Concern Over New Coronavirus Variant

NEW YORK (Reuters) – Mayor Bill de Blasio’s chief medical adviser on Thursday downplayed the results of two studies that may suggest a new coronavirus...

Liquid Biopsies Helpful in Prostate Cancer, but Most Not Ready for Routine Use

NEW YORK (Reuters Health) – Liquid biopsies have the potential to guide therapeutic decision making in prostate cancer, but issues such as assay standardization, cost...

Brazilian Researchers Tracking Reinfection by New Virus Variant

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Just as Brazil surpassed 200,000 deaths from COVID-19 on January 7,...

Gut Microbiome Predicts Nivolumab Efficacy in Gastric Cancer?

Preliminary data suggest that a certain pattern of gut microbes may be useful in predicting which patients with advanced gastric cancer are likely to benefit...

Differences in Right vs Left Colon in Black vs White Individuals

The right colon appears to age faster in Black people than in White people, perhaps explaining the higher prevalence of right-side colon cancer among Black...

Heavy Drinking by Teens May Affect White Matter Integrity

Heavy alcohol use in adolescence is linked to disruptions in white matter integrity, new research suggests. In a case control study of more than 400...

Gene Expression Different in Allergic, Irritant Contact Dermatitis

NEW YORK (Reuters Health) – Artificial intelligence (AI) can help identify biomarkers to distinguish between contact dermatitis (CD) due to allergic reactions or to irritants,...

Type 1 Diabetes Screen Costing $55 Is Launched in US

A new initiative launched by the diabetes charity JDRF aims to broaden screening for type 1 diabetes risk for the general population of the United...

First-in-Class ADC Has Benefit Across mTNBC Subgroups

The antibody–drug conjugate sacituzumab govitecan (SG) (Trodelvy) appears to be effective across biomarker subgroups for women with metastatic triple-negative breast cancer (mTNBC) that has progressed...

Low Plasma Transthyretin Linked to Risk of Heart Failure

Low plasma transthyretin, also known as prealbumin, is associated with incident heart failure in the general population, new research suggests. In two prospective, population-based studies...

Tildrakizumab for Psoriasis Shows Durable Efficacy Over 5 Years

The full 5-year results of a long-term extension study of tildrakizumab for psoriasis show a high rate of sustained disease control coupled with a favorable safety...

Improvements to Cancer Clinical Trials After COVID-19 Wreckage

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. As the COVID-19 pandemic rolled across North America earlier this year,...

New Technologies Aim to Improve Ovarian Cancer Detection

Encouraging trends abound in the management of ovarian cancer. As rates of ovarian disease continue to decline, there has also been a notable increase in...

Flavanols Effective for BP Lowering?

Dr Gunter Kuhnle A high intake of dietary flavanols, compounds found in plant-based foods, is associated with significantly lower systolic and diastolic blood pressure, new...

pCR in HER2+ Breast Cancer Predicts Long-Term Survival

A pathologic complete response (pCR) to targeted therapy in HER2-positive breast cancer portends good long-term outcomes, according to final results of the phase 3 NeoALTTO/BIG...