Tag: biologic therapy

Do Some Cancer Drugs Protect Against COVID-19?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Certain cancer drugs that lower levels of angiotensin-converting enzyme 2 (ACE2)...

Metformin Disappoints in Two Phase 2 Lung Cancer Trials

Although well tolerated, metformin does not improve survival when given alongside chemoradiotherapy to patients with locally advanced non–small cell lung cancer (NSCLC), and may even...

Three JAK Inhibitors Get Boxed Warnings, Modified Indications

The arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR) poses an increased risk of serious cardiac events such as heart attack or stroke, cancer,...

Should IBD Biologics Be Offered in Combination or as Monotherapy?

Adding or switching biologics is a common practice in the treatment of patients with inflammatory bowel disease (IBD), but there is a dearth of clinical...

Guidance on Additional COVID-19 Vaccine Dose for MS Patients

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Patients age 12 years and older with multiple sclerosis (MS) who...

‘Dawn of a New Era’ in the Treatment of Renal Cell Carcinoma

The decades-long search for a safe, effective adjuvant therapy for patients with resected kidney cancer at high risk of recurrence appears to have taken a...

Anti-Sperm Antibodies Tested as Contraceptive in Sheep

Antibodies that bind to sperm might be an effective nonhormonal method of contraception, at least according to early studies in sheep, researchers report. When researchers...

CAR T-Cell Therapy Drives Refractory SLE Into Remission

Chimeric antigen receptor T-cell (CAR T) therapy, a life-extending treatment for patients with advanced B-cell malignancies and multiple myeloma, has now been shown to be...

Antibody Prevents Malaria in New Trial

A new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to 9 months in people who were...

Biologics for Asthma Also Improve Chronic Rhinosinusitis

Biologics used as an asthma treatment also appear to improve symptoms of coexisting chronic rhinosinusitis in some patients, according to results from a real-world study...

New Guideline on Adolescent Urticaria

A new guideline from the European Academy of Allergy and Clinical Immunology (EAACI) recommends omalizumab as an add-on therapy for patients aged 12 to 17...

Liver Cancer Monotherapy Indication for Nivolumab Withdrawn

The indication for nivolumab (Opdivo) as monotherapy for hepatocellular carcinoma (HCC) for patients previously treated with sorafenib has been voluntarily withdrawn by the manufacturer, Bristol-Myers...

Monkeys May Lead the Way for Immunotherapy HIV Cure

A small study conducted in rhesus macaques found a 10-fold reduction in HIV viral load when the monkeys received immunotherapy to block programmed cell death...

Three New Drugs Implicated in ANCA-Associated Vasculitis

The overactive bladder treatment mirabegron (Myrbetriq) is one of three new drugs to be linked to cases of drug-associated antineutrophil cytoplasmic antibody–associated vasculitis (DA-AAV) according...

2 Sets of Guidelines Disagree

With two sets of Clostridioides difficile recommendations being published within a month of each other, clinicians may find themselves trying to reconcile some of the...

Diet Rich in Omega-3s Linked to Fewer Migraines, Less Pain

A diet rich in omega-3 fatty acids reduces the frequency and intensity of monthly migraine attacks, a new study suggests. In this interventional study, a...

Tislelizumab Benefit in HCC Undimmed by Prior Therapies

With the novel immunotherapy tislelizumab, durable responses are achieved for patients with advanced hepatocellular carcinoma (HCC), regardless of the number of prior lines of therapy,...

Iron-Clad Benefits of CRT Seen in Reduced-EF Heart Failure

The case for the use of intravenous iron therapy for some patients with heart failure (HF) and reduced ejection fraction (HFrEF) has strengthened in recent...

Rapid Core Antigen HCV Tests Could Expand Accessibility

A proposed rapid diagnostic test for hepatitis C viral infections that combines an inexpensive but lower-sensitivity core-antigen test with lab RNA confirmation of negative tests...

EC Approves Cemiplimab for Advanced or Metastatic BCC

The European Commission (EC) has approved cemiplimab (Libtayo) for the treatment of adults with locally advanced or metastatic basal cell carcinoma (BCC) who progressed on —...

New Guideline for Prevention, Diagnosis, and Treatment of C diff

The American College of Gastroenterology has issued new guidelines on management of Clostridioides difficile infection that now include roles for fecal microbial transplant (FMT), combination testing, and bezlotoxumab....

Biologic Treatment Mitigates PsA Risk in Patients With Psoriasis, Study Finds

Psoriasis patients treated with biological disease-modifying antirheumatic drugs had a significantly lower incidence of psoriatic arthritis (PsA) compared with those treated with phototherapy, in a...

Medicare Rule Changes Allow for Broader CGM Use

Medicare has made two changes that are expected to improve access to continuous glucose monitoring (CGM) devices for beneficiaries with diabetes. Beginning July 18, 2021,...

Good Response to COVID-19 Vaccine After HSCT and CAR T-cell Tx

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Patients with blood cancers are particularly vulnerable to COVID-19, and there...

Nasal Polyp Treatment Algorithm: Allergists, Surgeons Agree

Surgery precedes biologics but comes after saline irrigations and topical intranasal corticosteroids in a new treatment algorithm for US clinicians treating patients who have chronic...