Tag: biologic therapy

Medicare Rule Changes Allow for Broader CGM Use

Medicare has made two changes that are expected to improve access to continuous glucose monitoring (CGM) devices for beneficiaries with diabetes. Beginning July 18, 2021,...

Good Response to COVID-19 Vaccine After HSCT and CAR T-cell Tx

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Patients with blood cancers are particularly vulnerable to COVID-19, and there...

Nasal Polyp Treatment Algorithm: Allergists, Surgeons Agree

Surgery precedes biologics but comes after saline irrigations and topical intranasal corticosteroids in a new treatment algorithm for US clinicians treating patients who have chronic...

Rituximab Superior to Mycophenolate Mofetil in Pemphigus Vulgaris Study

Mycophenolate mofetil, commonly used as a first-line corticosteroid-sparing agent for moderate to severe cases of the autoimmune blistering skin condition pemphigus vulgaris, has been found...

COVID-19 Tied to Spike in Suspected Suicide Attempts by Girls

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Suspected suicide attempts by teenaged girls have increased significantly during the...

Moderna Seeks FDA OK for Adolescent COVID Vaccine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Moderna has filed for emergency use authorization from the U.S. Food...

One Quarter of 30–49-Year-Olds Have Abnormal Colonoscopy Results

More than one quarter of colonoscopies carried out in Americans aged 30 to 49 years reveal some type of neoplasm, and slightly over 6% of...

Immunotherapy Likely New Standard in Advanced Esophageal Cancer

Nivolumab (Opdivo) plus chemotherapy and nivolumab plus ipilimumab (Yervoy) were superior to standard chemotherapy in improving overall survival in patients with advanced esophageal squamous cell...

Lower Steroid Dose Proves Effective for New-Onset ANCA Vasculitis

A reduced dose of prednisolone plus rituximab was as effective as a conventionally high dose in treating patients with newly diagnosed antineutrophil cytoplasmic antibody (ANCA)–associated...

FDA Approves Ozanimod (Zeposia) for Ulcerative Colitis

The US Food and Drug Administration (FDA) has approved ozanimod (Zeposia) for adults with moderately to severely active ulcerative colitis (UC), the company has announced....

Microbiome Therapeutic Offers Protection Against Recurrent C diff

SER-109, an oral microbiome therapeutic, safely protects against Clostridioides difficile recurrence for up to 24 weeks, according to a recent phase 3 trial. Three days of treatment...

FDA OKs First Targeted Therapy for Subset of Patients With NSCLC

The US Food and Drug Administration (FDA) today granted an accelerated approval for amivantamab (Rybrevant) as the first targeted treatment for patients with non–small cell...

Ustekinumab Superior to Vedolizumab for Refractory Crohn’s

In a first direct comparison study, ustekinumab (Stelara, Janssen) emerged superior to vedolizumab (Entyvio, Takeda) on multiple measures of response and remission among patients with...

New Oral Protein Shows Promise for Ulcerative Colitis

A plant-based fusion protein is safe and effective for inducing favorable immune modulation in patients with mild to moderate ulcerative colitis with no immune suppression–side...

Antibiotic Cut ANCA-Vasculitis Infection Risk With Rituximab

The serious infection risk associated with rituximab treatment for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is high but can be offset by co-prescribing co-trimoxazole, data...

Fecal Transplantation Safe but Ineffective in PsA Trial

The first clinical trial of fecal microbiota transplantation in patients with psoriatic arthritis has found the procedure to be as safe as a sham procedure,...

Rituximab Benefits Seen in Neuropsychiatric Lupus

Patients with neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) seem to benefit from rituximab (Rituxan) therapy, according to data from the British Isles Lupus Assessment...

Some MS Treatments May Heighten COVID Risk

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. When it comes to SARS-CoV-2 infection among patients with multiple sclerosis...

Study Finds Psoriasis Associated With an Increased COVID-19 Risk

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. People with psoriasis have a higher risk of infection with COVID-19...

Bimekizumab Tops Adalimumab for Plaque Psoriasis

Bimekizumab bested adalimumab for moderate to severe plaque psoriasis in a phase 3 trial of adults from the agent’s maker UCB Pharma. The interleukin-17A (IL-17A)...

Should Biologics Be Used for Milder Cases of Psoriasis?

The remarkable efficacy of biologics for moderate-to-severe psoriasis has led some to ask if biologics should be used for milder cases. The issue was tackled...

Novel S1P-Receptor Modulator Shows Promise in Phase 2b AD Trial

A novel, highly selective oral sphingosine 1-phosphate (S1P)–receptor modulator showed promise as a treatment for atopic dermatitis (AD) in a 12-week phase 2b trial, according...

Tralokinumab Gets Nod for Atopic Dermatitis in Europe

On Friday, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) issued a positive opinion for the IL-13 inhibitor...

FDA Expands Use of SLIT Pollen Allergy Treatment to Children

The US Food and Drug Administration (FDA) has approved a new indication for ALK’s under-the-tongue immunotherapy tablet Ragwitek (Ambrosia artemisiifolia) to treat ragweed pollen-induced hay...

Ublituximab Plus Ibrutinib for CLL

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease associated with several known genetic abnormalities, including 17p deletion (del[17p]), 11q deletion (del[11q]), and TP53 gene...