Tag: biliary disease

MR Elastography Could Predict Cirrhosis in NAFLD

Liver stiffness measurement with magnetic resonance elastography (MRE) may prove predictive of future cirrhosis risk in patients with nonalcoholic fatty liver disease (NAFLD), according to...

The Risk Factors Behind Infected Pancreatic Necrosis’ Deadly Toll

Patients with infected pancreatic necrosis (IPN) are more likely to experience organ failure and mortality, which makes identifying them as quickly as possible especially crucial....

Novel Liver Dialysis Device May Safely Curb ACLF

An investigational liver dialysis device (DIALIVE) was associated with significantly greater survival of patients with acute-on-chronic liver failure (ACLF), compared with the standard of care...

Worse Survival With Recurrent AIH After Transplant

Autoimmune hepatitis that recurs following a liver transplant can impair both graft survival and overall survival, results of a large international study showed. Among 736...

Calories May Outweigh Nutrients in Diets for Fatty Liver

Intermittent calorie restriction offers only modest advantages over a low-carbohydrate, high-fat diet (LCHF) for treating nonalcoholic fatty liver disease (NAFLD), researchers say. The intermittent diet...

Waist Circumference Predicts Risk of Fatty Liver in Type 1 Diabetes

It follows that, as the prevalence of obesity among people with type 1 diabetes mellitus (T1DM) increases, so would the incidence of nonalcoholic fatty liver...

Obesity Amplifies Harmful Effects of Alcohol on the Liver

Being overweight or having obesity significantly increases the risk for liver disease and the likelihood of dying from it compared with being of normal weight, regardless...

Idiosyncratic Drug-Induced Liver Injury: New Guidelines

New guidelines from the American College of Gastroenterology on idiosyncratic drug-induced liver injury (DILI) emphasize that idiosyncratic DILI is increasingly driven by the burgeoning popularity...

Do Anti-ApoA-1 Antibodies Link Fatty Liver Disease and CVD?

Anti-apolipoprotein A-1 (ApoA-1) antibodies are common in non-alcoholic fatty liver disease (NAFLD) and may not only drive its development but also underlie the link between...

FDA Restricts Obeticholic Acid Over Serious Liver Injury Risk

The risk for serious liver injury with obeticholic acid (Ocaliva, Intercept Pharmaceuticals) has prompted the US Food and Drug Administration (FDA) to restrict its use...

Bariatric Surgery May Cut Cancer in Obesity With Liver Disease

In a large cohort of insured working adults with severe obesity and nonalcoholic fatty liver disease (NAFLD), among those who underwent bariatric surgery, the rate of...

Hepatotoxicity Risk Differs Between Psoriasis, PsA, and RA Patients

Patients taking methotrexate for psoriasis or psoriatic arthritis (PsA) were at a higher risk of developing liver disease than were patients with rheumatoid arthritis (RA)...

AASLD 2020: A Clinical News Roundup

Studies that address fundamental questions in hepatology and have the potential to change or improve clinical practice were the focus of a clinical debrief session...

NAFLD Prevalence Rising Among Children but Many Undiagnosed

(Reuters Health) – The incidence of nonalcoholic fatty liver disease (NAFLD) is rising among children, but not all youth with obesity are getting recommended screening,...

GLIMMER of Hope for Itch in Primary Biliary Cholangitis

Patients with primary biliary cholangitis experienced rapid improvements in itch and quality of life after treatment with linerixibat in a randomized placebo-controlled trial of the...

Trio Awarded Nobel Prize in Medicine for Discovering Hep C Virus

The Nobel Prize in Physiology or Medicine was awarded to two Americans and a British-born scientist this morning for the discovery of the hepatitis C...

Hepatocellular Carcinoma Shows Risk Factor Shift

Rates of hepatocellular carcinoma (HCC) continue to rise in the United States, but unevenly so given how the incidence has become highest in the Hispanic...

Fecal Transplant Shows Promise in Reducing Alcohol Craving

Fecal microbiota transplantation results in a short-term reduction in alcohol craving in patients with alcohol-induced cirrhosis who can’t stop drinking, results from a new study...

Terlipressin Squeaks by FDA Review for Hepatorenal Syndrome 1

The US Food and Drug Administration’s (FDA’s) Cardiovascular and Renal Drugs Advisory Committee narrowly recommended, by an 8-7 vote, that the agency grant marketing approval...

High Rate of Fatty Liver Disease Found in 9/11 Responders

First responders to the site of the 2001 World Trade Center attack may have an elevated risk of nonalcoholic fatty liver disease (NAFLD), according to...

COMMENTARY: Treating Liver Disease During COVID-19: New Recommendations

What your doctor is reading on Medscape.com: MAY 14, 2020 — The COVID-19 pandemic presents myriad challenges to hepatologists, gastroenterologists, transplant programs, primary...

See Acute Hepatitis? Consider COVID-19, NY Case Suggests

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A woman presented to the emergency department with high liver enzyme...