Tag: atherosclerosis

Ticagrelor Beneficial for Moderate Stroke: New THALES Analysis

For patients with a moderate-size stroke, benefit from ticagrelor plus aspirin was the same as for patients with minor stroke, a new exploratory analysis of...

South Asian Ancestry Linked to Increased Risk for Heart Disease

Individuals of South Asian ancestry face twice the risk of heart disease, compared with individuals of European descent, yet existing risk calculators fail to account...

Cardiology Journal Flags Papers Cited Hundreds of Times

A European cardiology journal has issued expressions of concern for seven widely-cited papers dating back to 2009 after a reader flagged suspicious images in the...

A1c Below Prediabetes Cutoff Linked to Subclinical Atherosclerosis

Hemoglobin A1c above 5% but below the prediabetes cutoff of 5.5% is an additional potential biomarker of subclinical atherosclerosis in people with low cardiovascular disease...

Do Anti-ApoA-1 Antibodies Link Fatty Liver Disease and CVD?

Anti-apolipoprotein A-1 (ApoA-1) antibodies are common in non-alcoholic fatty liver disease (NAFLD) and may not only drive its development but also underlie the link between...

Arthritis Drug May Curb Myocardial Damage in Acute STEMI

Early use of tocilizumab (Actemra) does not reduce myocardial infarct size but modestly increases myocardial salvage in patients with acute ST-segment elevation myocardial infarction (STEMI),...

Sickle-Cell Trait May Not Independently Elevate CHD Risk

African Americans with sickle-cell trait (SCT), that is, who are heterozygous for the sickle-cell gene variant, don’t as a result necessarily have an elevated risk...

Lp(a) and LPA Gene Score ‘Modest’ Predictors of CVD Risk

Although lipoprotein(a) (Lpa) levels and LPA genetic risk scores are both significantly associated with atherosclerotic cardiovascular disease (ASCVD) events, they appear to offer only a...

Calcium Burden Drives CV Risk Whether CAD Is Obstructive or Not

Coronary artery calcium (CAC) score as a measure of plaque burden more reliably predicts future cardiovascular (CV) risk in patients with suspected coronary disease (CAD)...

Chili Pepper Consumption Linked to Better Midlife Survival

In a meta-analysis of four geographically diverse observational studies, a higher intake of any type of chili pepper was associated with a lower rate of...

Clopidogrel Bests Ticagrelor for Elective PCI

Ticagrelor failed to unseat clopidogrel as the guideline-recommended P2Y12 inhibitor of choice in patients undergoing elective percutaneous coronary intervention for stable CAD in the randomized...

Simple Questionnaire Can Identify Silent Atherosclerosis

Individuals in the general population with high levels of silent coronary atherosclerosis can be successfully identified with a simple questionnaire that they can complete themselves...

Higher Serum Omega-3 Tied to Better Outcome After STEMI

Regular consumption of foods rich in omega-3 fatty acids was associated with improved prognosis after ST-segment myocardial infarction (STEMI) in a new observational study. The...

Steep, Sustained Lipid Reductions Over Statins With LIB003

The novel anti-PCSK9 compound LIB003 substantially reduces low-density lipoprotein (LDL) cholesterol levels over 52 weeks in patients already taking maximally tolerated statins, results of an...

Aspirin for Primary Prevention of CVD in Rheumatic Diseases

Low-dose aspirin may be considered for the primary prevention of cardiovascular disease (CVD) in patients with autoimmune systemic rheumatic diseases who are at particularly high...

Thrombectomy Alone Noninferior to Combination Therapy in Stroke

Endovascular thrombectomy alone was noninferior to thrombectomy plus thrombolysis with alteplase in terms of functional outcome for patients with large-vessel acute ischemic stroke in a...

No Benefit of Diabetes Drug Ertugliflozin in CV Outcomes Trial VERTIS

The sodium-glucose transporter 2 (SGLT-2) inhibitor ertugliflozin broke ranks with the other drugs in its class and failed to produce statistically significant drops in the...

Clopidogrel Adds No Benefit to Rivaroxaban+Aspirin

The VOYAGER PAD results from more than 6,500 patients created the biggest evidence base by far ever collected from patients with symptomatic peripheral artery disease...