Tag: aromatase inhibitor

Entinostat Doesn’t Overcome Endocrine Resistance in Breast Cancer

The histone deacetylase (HDAC) inhibitor entinostat failed to overcome resistance to endocrine therapy in hormone receptor–positive, HER2-negative, advanced breast cancer in a phase 3 trial....

One Strikeout, One Hit Against Low-Grade Serous Carcinomas

Two MEK inhibitors were tested against recurrent low-grade serous carcinomas of the ovaries, fallopian tubes, or peritoneum, but only one inhibitor offered clinical benefit over...

Cognitive Decline With Endocrine Tx for Breast Ca

Cognitive impairment seen in women with early breast cancer who undergo chemotherapy ― so-called chemobrain ― has now been reported in patients who are treated...