Tag: anemia

FDA OKs Belzutifan for Cancers Tied to von Hippel-Lindau Disease

The US Food and Drug Administration (FDA) approved belzutifan (Welireg) for adult patients with von Hippel-Lindau disease (VHL) who require therapy for associated renal cell...

Novel Liver Dialysis Device May Safely Curb ACLF

An investigational liver dialysis device (DIALIVE) was associated with significantly greater survival of patients with acute-on-chronic liver failure (ACLF), compared with the standard of care...

Luspatercept Benefit Also in Non-Transfusion-Dependent Thalassemia

The first-in-class erythroid maturation agent luspatercept (Reblozyl) is already approved for the treatment of anemia in adult patients with beta thalassemia who require red blood...

Vadadustat for Anemia in Chronic Kidney Disease: Questions Remain

Oral vadadustat, one of a new class of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs), is effective in the treatment of anemia in people with chronic...

Ublituximab Plus Ibrutinib for CLL

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease associated with several known genetic abnormalities, including 17p deletion (del[17p]), 11q deletion (del[11q]), and TP53 gene...

Made-to-Order TILs Effective Against Metastatic Melanoma

In just over one third of patients with metastatic melanoma who had experienced disease progression while receiving multiple prior lines of therapy, including immunotherapy and...

Maternal Chronic Conditions Predict Cerebral Palsy in Offspring

Several maternal chronic conditions increase the risk of giving birth to a child with cerebral palsy, based on data from more than 1.3 million Norwegian...

Durable Responses With Anti-BCMA CAR T-cell for Multiple Myeloma

For patients with heavily-pretreated multiple myeloma, the early and deep responses seen with the novel chimeric antigen receptor T-cell (CAR T-cell) construct ciltacabtagene autoleucel (cilta-cel)...

Multiple Sclerosis Prodrome Holds Promise of Earlier Diagnosis

“It is time that the prodromal phase of multiple sclerosis is formally recognized.” That was the conclusion of Helen Tremlett, PhD, delivering the opening plenary...

REALITY Trial Supports Restrictive Transfusion in Anemic MI

A restrictive blood transfusion strategy in myocardial infarction patients with anemia proved safe, significantly less costly, and at least as effective as the standard liberal...

Lockdown news: Covid has spelt a lockdown for routine health services | India News

There have been innumerable stories of the suffering of non-Covid patients across the country during the lockdown and after, and official data is now available...

All NSAIDs Raise Post-MI Risk but Some Are Safer: Next Chapter

Patients on antithrombotics after an acute myocardial infarction (MI) will face a greater risk for bleeding and secondary cardiovascular (CV) events if they start taking...

FDA Approves Olaparib for Certain Metastatic Prostate Cancers

The US Food and Drug Administration approved olaparib (Lynparza, AstraZeneca) for deleterious or suspected deleterious germline or somatic homologous recombination repair (HRR) gene-mutated metastatic castration-resistant...

COVID-19 in a Third-Trimester Pregnancy

What your doctor is reading on Medscape.com: MAY 09, 2020 — Initial Presentation A 26-year-old pregnant woman (gravida 3 para 1011) at...

EU Panel OKs Glasdegib for AML & Luspatercept for MDS

A new drug for acute myeloid leukemia (AML), glasdegib (Daurismo, Pfizer). is approaching approval in Europe. The drug was approved in the United States in...

FDA Approves Luspatercept for Anemia in MDS

The US Food and Drug Administration (FDA) has approved luspatercept (Reblozyl, Bristol-Myers Squibb/Acceleron) for the treatment of anemia in patients with myelodysplastic syndromes (MDS). The green light...