Tag: adverse effects

FDA’s Fast-Track Approval Exposed as Lax, in Need of Reform

Since the US Food and Drug Administration (FDA) established its accelerated drug approval pathway 28 years ago, more than 2 in 5 drugs granted fast-track...

Cryptococcal Meningitis: Single-Dose Regimen Noninferior

A single high dose of the antifungal agent liposomal amphotericin B (L-AmB; AmBisome, Gilead Sciences), with a background regimen of flucytosine and fluconazole, is noninferior...

New Treatment Option for Restless Legs?

The antiplatelet medication dipyridamole reduces motor and sensory symptoms of restless legs syndrome (RLS) and improves sleep duration for treatment-naive patients, results of a small, randomized,...

Half of Unvaccinated in US Unconcerned About Delta Variant: Poll

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. About half of unvaccinated or partially vaccinated Americans aren’t concerned about...

New Details of Myocarditis Linked to COVID Vaccines

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Further details from multiple cases of myocarditis linked to the Pfizer...

FDA to Add Myocarditis Warning to mRNA COVID-19 Vaccines

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The US Food and Drug Administration (FDA) is adding a warning...

Expert Offers 10 ‘Tips and Tricks’ for Everyday Cosmetic Practice

During the annual conference of the American Society for Laser Medicine and Surgery, H. Ray Jalian, MD, shared his “top 10” tips and tricks for...

Emerging Schizophrenia Drugs Target Negative Symptoms

Late-stage trials of new antipsychotic drugs are showing promise in the control of negative symptoms, according to an overview presented by Current Psychiatry and the...

Zanubrutinib Better Than Ibrutinib in CLL/SLL?

Zanubrutinib (Brukinsa), a second-generation Bruton tyrosine kinase (BTK) inhibitor, has shown a significantly greater delay in disease progression vs the standard of care ibrutinib (Imbruvica)...

EMA Seeks More Data on Myocarditis After COVID-19 Shots

The European Medicines Agency (EMA) safety committee is continuing its review of myocarditis and pericarditis following vaccination with COVID-19 vaccines. “Currently, further analysis is needed...

Nintedanib Slows Interstitial Lung Disease in Patients With RA

In a new subgroup analysis of a previously published multinational trial, the preservation of lung function with nintedanib (Ofev) was about the same in patients...

No Benefit in Cervical Cancer With Adjuvant Chemo

One of the top presentations at the top cancer meeting this year has negative results — but this abstract is “very important,” says Lori J....

Novel Drug Approved by FDA for Some Bile Duct Cancers

A novel drug, infigratinib (Truseltiq), is now available in the United States for adults with previously treated unresectable bile duct cancer harboring a fibroblast growth...

Early Start to Laser Treatment in Infants With Port Wine Stains

Treating port wine birthmarks with pulsed dye laser (PDL) can be safely done within the first few days after birth as an in-office procedure without any...

High Eradication, Fewer Side Events With Hybrid Therapy

A 14-day course of hybrid therapy was as effective as 10-day bismuth quadruple therapy, but with fewer side effects, according to results of a randomized...

Require Doctors Be COVID-19 Vaccinated?

Find the latest COVID-19 news and guidance in Medscape’s  Coronavirus Resource Center. Should COVID-19 vaccinations be required for healthcare providers? Most clinicians polled by Medscape...

New Oral Protein Shows Promise for Ulcerative Colitis

A plant-based fusion protein is safe and effective for inducing favorable immune modulation in patients with mild to moderate ulcerative colitis with no immune suppression–side...

Most Patients Labeled Penicillin-Allergic Really Aren’t

Most people whose medical record says they are allergic to penicillin are not actually intolerant, an allergist said Thursday during the first day of sessions...

Anticholinergic for Axillary Hyperhidrosis Shows Few Side Effects

Sofpironium bromide, a new topical anticholinergic agent, appears to be a safer version of glycopyrrolate for the treatment of axillary hyperhidrosis, according to 48-week safety and...

End Pause of J&J Vaccine, but Add Warning

Editor’s note: The FDA and CDC lifted the pause on the Johnson & Johnson vaccine on Friday evening, within hours of ACIP’s decision. Use of the...

FDA, CDC Lift Suspension of Johnson & Johnson Vaccine

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The US Food and Drug Administration (FDA) will add a warning...

Safety Profile for Novel CGRP Beats Standard of Care

Atogepant, an oral, small-molecule, calcitonin gene–related peptide receptor antagonist that’s been in development as a preventive treatment for chronic migraine, has been found to have...

J&J Pause Did Not Upend Vaccine Confidence: Poll

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The recommended pause on April 13 in the rollout of the...

Researchers Detail More Cases of Clots Tied to COVID Vaccines

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. New evidence emerged today tying vaccines for COVID-19 to extremely rare...

MS Hospital Visits Increase in Warmer Weather

Individuals with multiple sclerosis (MS) seek additional acute medical care during periods of unusually warm weather, a new study has found, raising concerns about possible...